Circular RNA in cholangiocarcinoma: A systematic review and bibliometric analysis

Zhou, Zhuping; Chen, Chaobo; Han, Bing; Wang, Yinyu; Liu, Yang; Liu, Qiaoyu; Xu, Xiaoliang; Yin, Yin; Sun, Beicheng

doi:10.1016/j.prp.2023.154755

Cited by 2 publications

(1 citation statement)

References 69 publications

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“…Examining distinct extracellular miRNA levels in plasma of O. viverrini- infected subjects compared to uninfected controls underscores their potential as non-invasive biomarkers. Circular RNAs (circRNAs) hold significant promise as markers for the initiation and advancement of CCA, presenting valuable prospects for diagnosis, therapeutic interventions, and prognostic surveillance of the disease [ 149 , 150 ]. In 2015, a finding emerged from plasma miRNA profiling, revealing the induction of eight miRNAs, namely hsa-miR-885-5p, hsa-miR-505-3p, hsa-miR-483-5p, hsa-miR-92b-3p, hsa-miR-874, has-miR-1307-3, hsa-miR-1275, and hsamiR-320b, associated with O. viverrini induced intrahepatic cholangiocarcinoma (Ov-iCCA) from tissue and plasma, thus laying the foundation for a circulating miRNA-based biomarker panel for Ov-CCA [ 151 ].…”

Section: Introductionmentioning

confidence: 99%

Current State of Knowledge on Blood and Tissue-Based Biomarkers for Opisthorchis viverrini-induced Cholangiocarcinoma: A Review of Prognostic, Predictive, and Diagnostic Markers

Kafle,

Suttiprapa

2024

Asian Pac J Cancer Prev

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Cholangiocarcinoma (CCA) is a prevalent cancer in Southeast Asia, with Opisthorchis viverrini ( O.viverrini ) infection being the primary risk factor. Most CCA cases in this region are diagnosed at advanced stages, leading to unfavorable prognoses. The development of stage-specific biomarkers for Opisthorchis viverrini -induced cholangiocarcinoma (Ov-CCA) holds crucial significance, as it facilitates early detection and timely administration of curative interventions, effectively mitigating the high morbidity and mortality rates associated with this disease in the Great Mekong region. Biomarkers are a promising approach for early detection, prognosis, and targeted treatment of CCA. Disease-specific biomarkers facilitate early detection and enable monitoring of therapy effectiveness, allowing for any necessary corrections. This review provides an overview of the potential O. viverrini -specific molecular biomarkers and important markers for diagnosing and monitoring Ov-CCA, discussing their prognostic, predictive, and diagnostic value. Despite the limited research in this domain, several potential biomarkers have been identified, encompassing both worm-induced and host-induced factors. This review offers a thorough examination of historical and contemporary progress in identifying biomarkers through multiomics techniques, along with their potential implications for early detection and treatment.

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Section: Introductionmentioning

confidence: 99%

Current State of Knowledge on Blood and Tissue-Based Biomarkers for Opisthorchis viverrini-induced Cholangiocarcinoma: A Review of Prognostic, Predictive, and Diagnostic Markers

Kafle,

Suttiprapa

2024

Asian Pac J Cancer Prev

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New Relevant Evidence in Cholangiocarcinoma Biology and Characterization

Porro,

Spínola-Lasso,

Pastore

et al. 2024

Cancers

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Among solid tumors, cholangiocarcinoma (CCA) emerges as one of the most difficult to eradicate. The silent and asymptomatic nature of this tumor, particularly in its early stages, as well as the high heterogeneity at genomic, epigenetic, and molecular levels delay the diagnosis, significantly compromising the efficacy of current therapeutic options and thus contributing to a dismal prognosis. Extensive research has been conducted on the molecular pathobiology of CCA, and recent advances have been made in the classification and characterization of new molecular targets. Both targeted therapy and immunotherapy have emerged as effective and safe strategies for various types of cancers, demonstrating potential benefits in advanced CCA. Furthermore, the deeper comprehension of the cellular and molecular components in the tumor microenvironment (TME) has opened up possibilities for new innovative treatment methods. This review discusses recent evidence in the characterization and molecular biology of CCA, highlighting novel possible druggable targets.

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Circular RNA in cholangiocarcinoma: A systematic review and bibliometric analysis

Cited by 2 publications

References 69 publications

Current State of Knowledge on Blood and Tissue-Based Biomarkers for Opisthorchis viverrini-induced Cholangiocarcinoma: A Review of Prognostic, Predictive, and Diagnostic Markers

Current State of Knowledge on Blood and Tissue-Based Biomarkers for Opisthorchis viverrini-induced Cholangiocarcinoma: A Review of Prognostic, Predictive, and Diagnostic Markers

New Relevant Evidence in Cholangiocarcinoma Biology and Characterization

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