Circulating adiponectin expression is elevated and associated with the IL-15/IL-15Rα complex in obese physically active humans

Pérez-López, Alberto; Valadés, David; Blanco, A I de Cos; García‐Honduvilla, Natalio; Martínez, Clotilde Vázquez

doi:10.23736/s0022-4707.18.09030-8

Cited by 5 publications

(2 citation statements)

References 45 publications

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“…However, no significant change was detected for IL-15 in older women after 12 weeks of RT (Urzi, Marusic, Licen, & Buzan, 2019). Furthermore, IL-15 was significantly lower in both obese and lean participants who perform physical activity regularly (≥180 min/week during the last year) than in sedentary obese and lean (Perez-Lopez et al, 2018). IL-7 is another myokine that is secreted by skeletal muscle as a key regulator of B-and Tcells differentiation (Ceredig & Rolink, 2012;Haugen et al, 2010).…”

Section: Introductionmentioning

confidence: 97%

Serum myokine levels after linear and flexible non‐linear periodized resistance training in overweight sedentary women

Nikseresht

Mohammadreza

Abdolhosein

et al. 2021

European Journal of Sport Science

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This study compared the capacity of linear-(LP) and non-linear periodized (NLP) resistance training to improve select myokines and metabolic parameters in overweight sedentary women. An additional purpose was to compare these variables between the overweight and lean women. Fitness-and agematched overweight women between 28 and 43 years old were randomly allocated to LP (body fat [BF]% = 38.7 ± 2.6, n = 10), NLP (BF% = 39.3 ± 2.4, n = 9) and control (BF% = 39.8 ± 2.6, n = 9) groups. Lean women (BF% = 29.1 ± 2.3, n = 16) matched for age and fitness were also included for baseline comparison. Resistance training programmes (12 weeks, 3 d.wk −1 , 9 exercises, 60-90% of 1repetition maximum [1RM]) were performed with different periodization schemes. Glucose, insulin, interleukin (IL)−7, IL-15, and insulin-like growth factor (IGF)−1 levels were measured at baseline and after training. Overweight subjects had significantly lower IL-15, IGF-1 and higher insulin, glucose, and insulin resistance (homeostasis model assessment, HOMA-IR) than lean subjects at baseline (all, P < .05). IL-15 and VO 2 max increased significantly after NLP compared with CON, which was accompanied by a significant decrease in HOMA-IR (all, P < .03). Muscular endurance improved significantly in both models after training compared to CON (all, P < .01), but it increased more in NLP than in LP (P = .01). Both training protocols were equally effective at reducing BF% and increasing IGF-1, IL-7, muscle mass and bench press 1RM (P < .01). It appears that LP and NLP are both effective strategies for improving health markers in overweight women, but LP is not as effective as NLP to improve IL-15, HOMA-IR and aerobic capacity. Highlights. Overweight women had a significantly lower IL-15 and IGF-1 compared to lean encounters, but no significant difference was noted for maximal strength, aerobic capacity, muscle mass, IL-7 and neutrophil/lymphocyte ratio. . Twelve weeks of either linear or flexible non-linear periodized resistance training resulted in reduction in BF% and neutrophil/lymphocyte ratio, and increased IGF-1, IL-7, muscle mass and bench press 1RM, with no difference between the two training protocols. . Linear protocol is not as effective as non-linear protocol to improve IL-15, HOMA-IR and aerobic capacity.

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Section: Introductionmentioning

confidence: 97%

Serum myokine levels after linear and flexible non‐linear periodized resistance training in overweight sedentary women

Nikseresht

Mohammadreza

Abdolhosein

et al. 2021

European Journal of Sport Science

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“…Interestingly, an increase in HMW-adiponectin concentration was observed after acute and chronic physical exercise with intensities ranging from moderate to vigorous ( 12 , 18–20 ). In addition, higher circulating adiponectin was reported in physically active compared to inactive individuals ( 21 ). Therefore, HMW-adiponectin is considered as a potential marker mediating the health-beneficial effects induced by physical exercise ( 14 ).…”

Section: Introductionmentioning

confidence: 99%

Integrated neuromuscular training intervention applied in schools induces a higher increase in salivary high molecular weight adiponectin and a more favorable body mass index, cardiorespiratory fitness and muscle strength in children as compared to the traditional physical education classes

Vasileva,

Font-Lladó,

Carreras-Badosa

et al. 2024

Front. Public Health

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BackgroundHigh-molecular-weight adiponectin (HMW-adiponectin) is a cardio-metabolic health protector. Objectives: (1) to compare body mass index (BMI), cardiorespiratory fitness (CRF) and muscle strength (MS) in healthy school-children depending on their baseline salivary-HMW-adiponectin concentration; and (2) to apply a 3-month integrated neuromuscular training (INT) and evaluate its effects on salivary-HMW-adiponectin concentration, BMI, CRF and MS in the same children. Additional goal: to identify if any potential changes during the 3-month period may be related to a potential change in salivary-HMW-adiponectin concentration.MethodsNinety children (7.4 ± 0.3 years) were recruited in primary schools and randomly allocated into control or intervention group. The intervention consisted of a 3-month INT applied during physical education (PE) classes, twice-weekly, while the control group had traditional PE classes. Body mass and height were measured, BMI was calculated and HMW-adiponectin was quantified in saliva. To assess CRF and MS, 800 m-run and hand-dynamometry were applied, respectively. All measurements were performed twice, at baseline and after 3 months.ResultsChildren with higher baseline salivary-HMW-adiponectin have more favorable BMI (p = 0.006) and slightly higher CRF (p = 0.017) in comparison to the children with lower baseline salivary-HMW-adiponectin. There were no big changes after the 3-month-period neither in the control, nor the INT group. However, it is worthy to note that the INT induced slightly higher increase in salivary-HMW-adiponectin (p = 0.007), and a slightly higher improvement in BMI (p = 0.028), CRF (p = 0.043) and MS (p = 0.003), as compared to the traditional PE classes. Finally, the INT-induced improvement in CRF was associated with the increased post-salivary-HMW-adiponectin concentration (p = 0.022).ConclusionMain findings may suggest the potential utility of an INT as a cost-effective strategy that can be applied in schools to induce cardio-protective effects in school-children.

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Adiponectin, Diabetes, and the Cardiovascular System

Gasbarrino

Boutari

Filippaios

et al. 2023

Contemporary Cardiology

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Circulating adiponectin expression is elevated and associated with the IL-15/IL-15Rα complex in obese physically active humans

Cited by 5 publications

References 45 publications

Serum myokine levels after linear and flexible non‐linear periodized resistance training in overweight sedentary women

Serum myokine levels after linear and flexible non‐linear periodized resistance training in overweight sedentary women

Integrated neuromuscular training intervention applied in schools induces a higher increase in salivary high molecular weight adiponectin and a more favorable body mass index, cardiorespiratory fitness and muscle strength in children as compared to the traditional physical education classes

Adiponectin, Diabetes, and the Cardiovascular System

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