Circulating IGF-I in plasma of growing male and female turkeys of medium and heavy weight lines

Bacon, Wayne L.; Nestor, Karl E.; Emmerson, D. A.; Vasilatos‐Younken, R.; Long, David P.

doi:10.1016/0739-7240(93)90031-6

Cited by 22 publications

(12 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The decline with age occurred later in males than females (13 weeks vs. 8 weeks) and also later than in Pekin ducks (about 6-7 weeks of age) which display faster growth rate [9]. This difference induced higher circulating IGF-I levels in males than in females between 7 and 12 weeks of age, which is consistent with the results obtained in Pekin ducks [9] and turkeys [2]. By contrast, male chickens have been reported to have lower concentrations of IGF-I than females at early ages (first 3 weeks post-hatch), and not to differ from females at later ages [14].…”

Section: Discussionsupporting

confidence: 81%

“…Lower concentrations of IGF-I were observed in male than female chickens at early ages (first 3 weeks posthatch), while no difference occurred at later ages [14]. Higher IGF-I concentrations were described in male compared to female growing turkeys [2] and Pekin ducks [9]. Then, the aim of our study was to investigate the effects of sex and age on the circulating concentrations of T3, GH and IGF-I in male and female Muscovy ducks from 1-d old to 15 weeks of age.…”

Section: Introductionmentioning

confidence: 83%

See 1 more Smart Citation

Sexual dimorphism for growth in Muscovy ducks and changes in insulin-like growth factor I (IGF-I), growth hormone (GH) and triiodothyronine (T3) plasma levels

et al. 2001

View full text Add to dashboard Cite

-Muscovy ducks display marked sexual dimorphism for body weight. The aim of our study was to analyse the possible relationships between this dimorphism and plasma levels of T3, GH and IGF-I from hatch to 15 weeks of age. We found no significant effect of sex or age on plasma T3 which remained relatively stable about 6 nM . L -1 . Plasma GH levels were highest (14-24 ng . mL -1 ) but highly variable during the first four weeks in females and during the first seven weeks in males. Then, they decreased and remained low (3-4 ng . mL -1 ) until the age of 15 weeks. A trend for higher GH concentrations in males compared to females was observed across the experimental period. The difference was maximum around 6-7 weeks of age. Plasma IGF-I levels rose sharply between 2 and 3 weeks of age and remained high until 6-7 weeks of age for the females and 13 weeks of age for the males then started to decrease. For the whole experimental period, significantly higher IGF-I levels were measured in males. The differences between sexes were significant between 7 and 12 weeks of age and at 14 weeks of age. The differences in circulating GH and IGF-I levels between sexes suggest that the somatotrophic axis is implicated in Muscovy duck sexual dimorphism. sex / dimorphism / GH / IGF-I / T3 / duckRésumé -Dimorphisme sexuel du canard de Barbarie et variation des concentrations plasmatiques en IGF-I, GH et T3. Le canard de Barbarie présente un dimorphisme sexuel sur le poids vif assez prononcé. L'objectif de la présente étude était d'analyser les relations éventuelles entre ce dimorphisme et les concentrations plasmatiques de T3, GH et IGF-I depuis l'éclosion jusqu'à l'âge de 15 semaines. Aucun effet significatif du sexe ou de l'âge n'est mis en évidence sur le taux circulant de T3 qui reste stable à environ 6 nM . L -1 . Le taux circulant de GH est très élevé et très variable au cours des quatre premières semaines chez les femelles et des sept premières semaines chez les mâles. Il décroît ensuite pour atteindre 3-4 ng . mL -1 à partir de 9-10 semaines jusqu'à l'âge de 15 semaines. Sur l'ensemble de la période expérimentale, les mâles présentent un taux circulant de GH significativement Reprod. Nutr. Dev. 41 (2001) [173][174][175][176][177][178][179] 173

show abstract

Section: Discussionsupporting

confidence: 81%

Section: Introductionmentioning

confidence: 83%

Sexual dimorphism for growth in Muscovy ducks and changes in insulin-like growth factor I (IGF-I), growth hormone (GH) and triiodothyronine (T3) plasma levels

et al. 2001

View full text Add to dashboard Cite

show abstract

“…Insulin-like growth hormone 1 (IGF-1) was mapped by IPA into the RhoA signaling pathway. This protein, structurally similar to insulin, acts via either autocrine or paracrine mechanisms (McMurtry et al, 1997) and regulates tissue growth and development in various vertebrates (Jones and Clemmons, 1995), including turkeys (Bacon et al, 1993;Richards et al, 2005). Infusion of IGF-1 into chicken has been shown to affect protein synthesis (Conlon and Kita, 2002) and mediate protein degradation (Czerwinski et al, 1998;Tomas et al, 1998).…”

Section: Rhoa Signaling and Actin Cytoskeleton Signaling Pathwaymentioning

confidence: 99%

Differential gene expression between normal and pale, soft, and exudative turkey meat

Malila¹,

Tempelman

Sporer

et al. 2013

Poultry Science

View full text Add to dashboard Cite

“…Tal ocorrência poderia estar associada ao fato de que alguns estudos demonstram diferenças significativas na abundância de mRNA dos fatores de crescimento semelhantes à insulina entre machos e fêmeas. Bacon et al (1993), investigando os níveis plasmáticos de IGF-I circulante em perus de diferentes sexos geneticamente selecionados para alta e média taxa de ganho de peso corporal, observaram que esta proteína está positivamente correlacionada a taxas de crescimento no período neonatal (1-7 semanas de idade), mas não relacionada ao crescimento em machos e negativamente correlacionada ao crescimento de fêmeas de 8 a 28 semanas de idade (BACON et al, 1993). Assim, estudos adicionais devem ser conduzidos a fim de testar uma possível correlação entre variações no padrão de expressão do gene IGF-II em embriões de aves de diferentes sexos.…”

Section: Resultsunclassified

Detecção Dos Transcritos Do Fator De Crescimento Igf-Ii Em Tecidos De Aves

Gabriel

Coutinho²

2005

Rev. Acad. Cien. Anim.

View full text Add to dashboard Cite

Os fatores de crescimento semelhantes à insulina (IGFs) são agentes críticos que regulam positivamente importantes vias de proliferação e diferenciação celular envolvidas no crescimento animal. O objetivo do presente estudo foi detectar transcritos do gene IGF-II durante o desenvolvimento fetal e pós-natal de galinha por análises de RT-PCR. RNA total foi extraído a partir de embriões inteiros de galinha em diferentes estádios de desenvolvimento e de tecidos hepático, muscular e adiposo de uma ave com 3 semanas de idade. Inicialmente, a primeira fita de cDNA foi obtida por ensaios de transcrição reversa a partir de amostras de RNA total na presença da enzima transcriptase reversa. Posteriormente, reações em cadeia da polimerase foram realizadas a fim de amplificar seqüências correspondentes ao gene IGF-II empregando “primers” específicos e uma DNA polimerase. Nossos resultados demonstraram a presença de fragmentos do fator IGF-II em todos os estádios de desenvolvimento analisados. Entretanto, sinais de amplificação desse gene não foram observados nos tecidos hepático, muscular e adiposo em nossas condições experimentais. As descobertas apresentadas no presente estudo reforçam evidências descritas em mamíferos, demonstrando que a ação do gene IGF-II é potencialmente induzida em distintas fases do desenvolvimento embrionário de aves, em contraste aos baixos efeitos exibidos sobre o crescimento pós-natal.

show abstract

Circulating IGF-I in plasma of growing male and female turkeys of medium and heavy weight lines

Cited by 22 publications

References 27 publications

Sexual dimorphism for growth in Muscovy ducks and changes in insulin-like growth factor I (IGF-I), growth hormone (GH) and triiodothyronine (T3) plasma levels

Sexual dimorphism for growth in Muscovy ducks and changes in insulin-like growth factor I (IGF-I), growth hormone (GH) and triiodothyronine (T3) plasma levels

Differential gene expression between normal and pale, soft, and exudative turkey meat

Detecção Dos Transcritos Do Fator De Crescimento Igf-Ii Em Tecidos De Aves

Contact Info

Product

Resources

About