Circulating Markers in Gastroenteropancreatic Neuroendocrine Tumors (GEP NETs)

Massironi, Sara; Spampatti, Matilde Pia; Rossi, Roberta; Conte, Dario; Ciafardini, C.; Cavalcoli, Federica; Peracchi, M.

doi:10.5772/33959

Cited by 1 publication

(1 citation statement)

References 18 publications

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“…Although primary breast NET (2-5%) is rarely seen in the literature, different from this study, primary gastric NET was found at a rate of 14% (Tavassoli and Devilee, 2003;Hauso et al, 2008;Yao et al, 2013). Stains such as chromogranin A, synaptophysin, and NSE are among the examples of immunohistochemical stains that are used in the differential diagnosis of patients with NET (Zjačić-Rotkvić and Berković, 2010; Stojsic et al, 2011;Massironi et al, 2012). There are studies defending that there is a correlation between the staining characteristics of the tumor and the grade of the tumor.…”

Section: Discussionmentioning

confidence: 67%

Survival Analysis and Prognostic Factors for Neuroendocrine Tumors in Turkey

Yücel

Babacan²,

Kaçan³

et al. 2013

Asian Pacific Journal of Cancer Prevention

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1-90 months). The three-year overall survival rate was 71%: 100% in stage I, 88% in stage II, 80% in stage III, and 40% in stage IV. The three-year survival rate was 78% in tumors localized in the gastroenteropancreatic region, and 54% in tumors localized in other organs. In the univariate analysis, gender, age, performance status of the patients, grade, localization, surgical treatment, and neutrophil/ lymphocyte ratio (≤5 versus >5) affected the prognosis of the patients. Conclusions: Most of the tumors were localized in the gastroenteropancreatic region, and the three-year survival rate in tumors localized in this region was better than the tumors localized in other sites. Surgical treatment was a positive independent prognostic factor, whereas Grade 3 and a neutrophil/lymphocyte ratio of >5 were negative independent prognostic factors.

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