Abstract. In this work, we provide an extensive inventory of Pb and Nd radiogenic isotopes in surface sediments from the Southwestern Atlantic margin, aiming to interpret the role played by ocean circulation in sediment distribution. There are latitudinal trends for Pb and Nd isotopes, reflecting the different current systems acting on the margin. The utilization of sediment fingerprinting allowed us to associate the isotopic signatures to the main oceanographic forcings in the area. We recognized differences between the Nd and Pb sources for the sediments to the Argentinean shelf, carried by the Subantarctic Shelf Water, and slope, transported by deeper flows. Sediments from Antarctica extend up to the Uruguayan margin, carried by the Upper- and Lower Circumpolar Deep Water. Our data confirm that, for shelf and intermediate (up to 1,200 m water depth) areas, the transfer of sediments from the Argentinean margin to the North of 35° S is limited by the Subtropical Shelf Front and the recirculated Antarctic Intermediate Water. On the southern Brazilian margin, it is possible to recognize the northward influence of the Río de la Plata sediments carried by the Plata Plume Water. This influence is limited by the southward flow of waters transported by the Brazil Current. Finally, we propose that the Subtropical Shelf Front and the Santos Bifurcation act as boundaries of geochemical provinces in the area. Finally, a qualitative model of sediment sources and transport is provided for the Southwestern Atlantic margin.