Circulation of Influenza A(H5N8) Virus, Saudi Arabia

Al-Ghadeer, Hussain Mohammed; Chu, Daniel K.W.; Rihan, Ehab M A; Abd-Allah, Ehab A; Gu, Haogao; Chin, Alex W. H.; Qasim, Ibrahim; Al-Doweriej, Ali; Alharbi, Sanad; Al-Aqil, Marshad A; AL-Sahaf, Ali; Rahman, Salah S Abdel; Aljassem, Ali H; Abdul-Al, Ali; Aljasir, Mohammed R; Alhammad, Yousef M O; Kasem, Samy; Peiris, Malik; Zaki, Ahmed Z S .A.; Poon, Leo L. M.

doi:10.3201/eid2410.180846

Cited by 9 publications

(13 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The internal gene segments of the EG/P2-29 showed no identity with any of the currently available H6N2 viruses on the GISAID platform indicating that a LPAIV H6N2 virus with novel gene constellation has been detected. Notably, the Pb2 and PB1 segments of the Egyptian EG/P2-29 virus shared common ancestors (A/barnacle goose/Netherlands/2/2014(H3N6) for the PB2 and A/ duck/Hubei/ZYSYG3/2015(H6N2) for PB1) with recently HPAIV H5N5 in Europe and HPAIV H5N8 in Saudi Arabia respectively (Al-Ghadeer et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Avian influenza virus surveillance in migratory birds in Egypt revealed a novel reassortant H6N2 subtype

Zanaty¹,

Erfan²,

Mady³

et al. 2019

Avian Res

View full text Add to dashboard Cite

Background: Avian influenza viruses (AIVs) have been identified from more than 100 different species of wild birds around the globe. Wild migratory birds can act as potential spreaders for AIVs to domestic birds between different countries. Egypt is situated on important migratory flyways for wild birds between different continents. While much is known about circulation of zoonotic potential H5N1 and H9N2 AIVs in domestic poultry in Egypt, little is known about the pivotal role of migratory birds in the maintenance and transmission of the viruses in Egypt.

show abstract

Section: Discussionmentioning

confidence: 99%

Avian influenza virus surveillance in migratory birds in Egypt revealed a novel reassortant H6N2 subtype

Zanaty¹,

Erfan²,

Mady³

et al. 2019

Avian Res

View full text Add to dashboard Cite

show abstract

“…In 2016 and 2019, the HPAI H5N8 virus caused successive epidemics in Nigeria, Cameroon, Egypt, Saudi Arabia and Namibia [ 12 – 17 ]. An increasing number of reports indicate that HPAI H5N8 viruses continuously cause deaths in wild migratory birds and birds in live poultry markets [ 18 – 20 ].…”

Section: Introductionmentioning

confidence: 99%

“…]. An increasing number of reports indicate that HPAI H5N8 viruses continuously cause deaths in wild migratory birds and birds in live poultry markets [18][19][20].…”

mentioning

confidence: 99%

Development and evaluation of a TaqMan MGB RT-PCR assay for detection of H5 and N8 subtype influenza virus

Yang,

Xu,

Liu

et al. 2020

BMC Infect Dis

View full text Add to dashboard Cite

Background: Highly pathogenic influenza A (H5N8) viruses have caused several worldwide outbreaks in birds and are of potential risk to humans. Thus, a specific, rapid and sensitive method for detection is urgently needed. Methods: In the present study, TaqMan minor groove binder probes and multiplex real-time RT-PCR primers were designed to target the H5 hemagglutinin and N8 neuraminidase genes. A total of 38 strains of avian influenza viruses and other viruses were selected to test the performance of the assay. Results: The results showed that only H5 and N8 avian influenza viruses yielded a positive signal, while all other subtypes avian influenza viruses and other viruses were negative. High specificity, repeatability, and sensitivity were achieved, with a detection limit of 10 copies per reaction. Conclusions: The developed assay could be a powerful tool for rapid detection of H5N8 influenza viruses in the future.

show abstract

“…Currently, 16 haemagglutinin (HA) and 9 neuraminidase subtypes of influenza viruses infect birds. 1 Highly pathogenic AIVs (HPAIV) are usually associated with H5 and H7 subtypes while the other subtypes are mainly low pathogenic avian influenza. HPAIV subtypes H5N1 and H5N8 were recently reported in poultry populations in many countries in the Middle East and Asia including Saudi Arabia, Iran, Lebanon, Iraq, Bangladesh and India.…”

Section: Introductionmentioning

confidence: 99%

“…Avian influenza viruses (AIVs) belong to the family Orthomyxoviridae. Currently, 16 haemagglutinin (HA) and 9 neuraminidase subtypes of influenza viruses infect birds 1. Highly pathogenic AIVs (HPAIV) are usually associated with H5 and H7 subtypes while the other subtypes are mainly low pathogenic avian influenza.…”

Section: Introductionmentioning

confidence: 99%

Molecular characterisation of an avian influenza (H5N8) outbreak in backyard flocks in Al Ahsa, Eastern Saudi Arabia, 2017–2018

Hemida¹,

Chu

Abdelaziz

et al. 2019

Veterinary Record Open

View full text Add to dashboard Cite

BackgroundAvian influenza viruses are still causing major concern not only to the poultry industry but also to human health across the globe. The live poultry markets and the small-scale local breeding of various species of birds in backyards are still playing important roles in the sustainability of most virulent influenza viruses, especially H5N8.MethodsThe authors investigated an outbreak of highly pathogenic avian influenza H5N8 in backyard flocks in Al Ahsa, Eastern Saudi Arabia that occurred in 2017–2018.ResultsA range of poultry including chickens, ostriches, ducks, pigeons and turkeys were clinically affected. Phylogenetic analysis suggested that this was a common source outbreak caused by a virus closely related to H5N8 viruses causing outbreaks elsewhere in Saudi Arabia in early 2018.ConclusionsSmall backyard flocks are still contributing to the epidemiology and transmission of H5N8.

show abstract

Circulation of Influenza A(H5N8) Virus, Saudi Arabia

Cited by 9 publications

References 9 publications

Avian influenza virus surveillance in migratory birds in Egypt revealed a novel reassortant H6N2 subtype

Avian influenza virus surveillance in migratory birds in Egypt revealed a novel reassortant H6N2 subtype

Development and evaluation of a TaqMan MGB RT-PCR assay for detection of H5 and N8 subtype influenza virus

Molecular characterisation of an avian influenza (H5N8) outbreak in backyard flocks in Al Ahsa, Eastern Saudi Arabia, 2017–2018

Contact Info

Product

Resources

About