Circulation of rare events in the liquid biopsy for early detection of lung mass lesions
Karen Resnick,
Anya Shah,
Jeremy Mason
et al.
Abstract:BackgroundLung cancer screening with low‐dose computed tomography (CT) scans (LDCT) has reduced mortality for patients with high‐risk smoking histories, but it has significant limitations: LDCT screening implementation remains low, high rates of false‐positive scans, and current guidelines exclude those without smoking histories. We sought to explore the utility of liquid biopsy (LBx) in early cancer screening and diagnosis of lung cancer.MethodsUsing the high‐definition single‐cell assay workflow, we analyzed… Show more
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