Circumscribed Plantar Hypokeratosis

Non-Invasive Diagnosis of Angioma Serpiginosum Plantaris: High-Resolution Dermoscopy, High-Frequency Ultrasound, and Line-Field Confocal Optical Coherence Tomography

“…Circumscribed palmar or plantar hypokeratosis (CPH) is a rare, acquired epidermal malformation similar to AS, which is frequently observed in women but between the ages of 40 and 80 years. The clinical examination of CPH usually reveals a rounded, well-circumscribed erythematous depressed lesion with a slightly raised scaly border [28]. The dermoscopy of CPH shows a "ragged" border, mild erythema, some engorged blood vessels and white macules on the base of lesion, with overlying white streaks [29].…”

“…To the best of our knowledge, this is the first case of AS presenting as a unique small plantar lesion, occurring during adolescence, and investigated with combined non-invasive imaging, such as HRVD, HFUS, and LC-OCT [24][25][26][27][28]. Further investigations into other cases are desirable to confirm the present findings, describing these new observations in a case with unconventional clinical patterns and trauma-induced etiology contribute to our broader understanding of the dermatological presentations of AS at the plantar site.…”