Cirrhotic Cardiomyopathy – a significant complication of Chronic Liver Disease Patients

Mahant, Seema; Chandel, Nirupama; Upasana, Upasana; Mahant, P; Kumbhakar, T

doi:10.9790/0853-13763538

Cited by 2 publications

(1 citation statement)

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“…Our study population showed predominance of male patients (82%) (Table 2) indicating that cirrhosis is more prevalent among them which was in accordance with other authors. 9,10 Most common etiology of cirrhosis was alcohol (41%), but distribution of alcoholic patients was even in the 3 MELD groups (P value: .223) (Table 2). Prevalence of CCM in our study was 48%.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Cardiac Dysfunction in Cirrhosis and Its Relation With Meld Score

Kumar

Bansal

Bery

et al. 2022

Indian Journal of Clinical Medicine

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Background: Cardiac structural and functional abnormalities have been described in patients of liver cirrhosis. The constellation of these abnormalities is termed as cirrhotic cardiomyopathy (CCM) and its prevalence remains unknown, mostly because the disease is latent and shows itself when the patient is subjected to stress. This study was designed to evaluate the prevalence of cardiac dysfunction in patients of liver cirrhosis and to analyze its relation with model for end-stage liver disease (MELD) score. Methods: Hundred patients of liver cirrhosis were enrolled for the study and divided into 3 groups according to MELD score: ≤9, 10-19, and ≥20. All study participants underwent detailed cardiac assessment with Doppler echocardiography. Prevalence of cardiac dysfunction and its relation with MELD score was determined. Results: Prevalence of CCM and diastolic dysfunction (DD) was 48% and 30%, respectively. A total of 82%, 59%, and 50% patients had prolonged corrected QT interval (QTc), isovolumic relaxation time (IVRT), and deceleration time (DT), respectively. Prevalence of CCM, DD and prolonged QTc, IVRT, and DT had significant correlation with MELD score ( P < .05). Conclusion: Patients with cirrhosis had impaired cardiac function, mainly present as CCM and DD, and the extent of dysfunction was correlated with the MELD score. Hence, MELD scoring system can be used to predict risk of occurrence of cardiac dysfunction in cirrhosis.

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Section: Discussionmentioning

confidence: 99%