“…The management of oncological patients has changed profoundly and, although the main goal is overall survival (OS), new knowledge of the molecular cancer profile and the development of new pharmacologic treatments has led to the use of surrogate end-points to measure interim treatment efficacy [ 1 , 2 , 3 , 4 , 5 , 6 , 7 ] related to the disease setting, including disease-free (DF), recurrence-free (RF), and progression-free survival (PFS) [ 8 , 9 , 10 , 11 , 12 ]. In this context, interventional radiology (IR), especially ablation treatment, is one of the most rapidly growing areas in oncology [ 13 , 14 , 15 , 16 ]. Its success is essentially due to the minimally invasive nature of the treatment with lower complication rates and superior toxicity profiles, and often with comparable or superior mid- and long-term oncologic outcomes compared to conventional therapies, such as surgical procedures or systemic treatments [ 17 , 18 , 19 , 20 ].…”