cis-Palladium(II) complexes of derivatives of di-(2-pyridyl)methane: Study of the influence of the bridge group in the coordination mode

Andrade‐López, Noemí; Alvarado‐Rodríguez, José G.; González‐Montiel, Simplicio; Rodríguez-Méndez, María Guadalupe; Páez-Hernández, María Elena; Galán-Vidal, Carlos Andrés

doi:10.1016/j.poly.2007.06.006

Cited by 19 publications

(8 citation statements)

References 23 publications

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“…The dihedral angle θ (N1–N2–Cl1–Cl2) of the complexes (1.48° for L 2 PtCl 2 , –1.96° for L 3 PtCl 2 ) is slightly larger. The bond lengths and angles are almost identical to the values found in the unsubstituted complex L 1 PtCl 2 and previously reported analogues . In summary, it can be said that the variation of steric load caused by a varying number of methyl groups in the ligand backbone has no significant influence on the molecular structure in the solid state.…”

Section: Resultssupporting

confidence: 85%

“…For the platinum complexes L 1 PtCl 2 – L 3 PtCl 2 , the 195 Pt signals can be found between δ = –397 and –556 ppm (relative to K 2 PtCl 4 ) and are characteristic for platinum in the +II oxidation state in an [N 2 Cl 2 ] coordination sphere . Again, a set of two signals can be found in the case of L 2 PtCl 2 , at δ = –432 and –555 ppm, respectively.…”

Section: Resultsmentioning

confidence: 89%

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Antiproliferative Copper(II) and Platinum(II) Complexes with Bidentate N,N‐Donor Ligands

et al. 2017

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Three copper(II) complexes of a series of bidentate dipyridylmethane ligands, as well as their structurally related platinum(II) analogues, have been synthesised and fully characterised to evaluate their coordination chemistry and antiproliferative properties. New crystal structures of the complexes L3CuCl2, L2PtCl2 and L3PtCl2, where L2, L3 have one and two methyl substituents on the bridgehead carbon atom between the coordinated pyridine ligands, respectively, were obtained. The in vitro cytotoxicity of the free ligands and their corresponding platinum and copper complexes was evaluated in the cisplatin‐sensitive ovarian teratocarcinoma cell line CH1/PA1, as well as in rather cisplatin‐insensitive colon (SW480) and lung (A549) carcinoma cells, using the MTT assay. All six complexes showed higher cytotoxicity than the ligands L1–L3 alone, giving IC50 values in the low micromolar range.

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Section: Resultssupporting

confidence: 85%

Section: Resultsmentioning

confidence: 89%

Antiproliferative Copper(II) and Platinum(II) Complexes with Bidentate N,N‐Donor Ligands

et al. 2017

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“…In these complexes, the metallic coordination affects mainly the chemical shifts of the neighboring carbon atoms to the coordinate nitrogen atoms (C2 is shielded and C6 is deshielded). 20 These data and the magnetic equivalence of the pyridine rings of the dipyridine fragment suggest the formation of symmetrical palladium and platinum complexes with six-membered chelate rings.…”

Section: Synthesis Of Ligands 1 Andmentioning

confidence: 91%

“…[9][10][11][12][13][14][15][16] In other dipyridines with less flexible bridging groups, the formation of five-membered rings (Ic) has been reported. 17,18 Recently, we described the synthesis of complexes of Li(I) 19 and Pd(II) 20 and the formation of five-membered rings by the use of the di- …”

Section: Introductionmentioning

confidence: 99%

Synthesis and crystal structures of cis-palladium(II) and cis-platinum(II) complexes containing dipyridyl ligands

Andrade‐López¹,

Alvarado‐Rodríguez²,

González‐Montiel³

et al. 2007

Arkivoc

Self Cite

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Coordinative behavior of the di-(2-pyridyl)hydroxymethane (1) and di-(2-pyridyl)-2-pyridylsulfanylmethane (2) ligands towards Pd(II) and Pt(II) is described. The compounds 3-5 were characterized by IR, mass spectrometry and NMR spectroscopy. Crystal structures of [Pt{(C 5 H 4 N) 2 CH(OH)}Cl 2 ] 3 and [Pd{(C 5 H 4 N) 2 CH(2-C 5 H 4 NS)}Cl 2 ] 4 as DMSO solvates displayed the formation of neutral mononuclear complexes. In the complexes 3 and 4 is observed the formation of six-membered chelate rings. The local geometry of the metallic atoms can be described as square planar in the title complexes.

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“…Some of these complexes, especially the trans analogs with nonplanar heterocyclic amine ligands, have been found to overcome multifactorial cisplatin resistance in human ovarian cell lines [5,6]. On the other hand, Pd(II) complexes have been widely explored due to their catalytic efficiency, e.g., for various carbon-carbon and carbon-nitrogen bond-forming reactions [7][8][9][10][11]. While most studies of palladium have concentrated on the reactivity of its complexes, little information about their electronic structures has been obtained.…”

Section: Introductionmentioning

confidence: 99%

Spectroscopic, structure and DFT studies of palladium(II) complexes with pyridine-type ligands

Małecki

Maroń

2011

Transition Met Chem

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Five palladium(II) complexes with pyridine derivative ligands have been synthesized. The molecular structures of the complexes were determined by X-ray crystallography, and their spectroscopic properties were studied. Based on the crystal structures, computational investigations were carried out in order to determine the electronic structures of the complexes. The electronic spectra were calculated with the use of time-dependent DFT methods, and the electronic spectra of the transitions were correlated with the molecular orbitals of the complexes. The emission properties of the complexes have been examined.

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cis-Palladium(II) complexes of derivatives of di-(2-pyridyl)methane: Study of the influence of the bridge group in the coordination mode

Cited by 19 publications

References 23 publications

Antiproliferative Copper(II) and Platinum(II) Complexes with Bidentate N,N‐Donor Ligands

Antiproliferative Copper(II) and Platinum(II) Complexes with Bidentate N,N‐Donor Ligands

Synthesis and crystal structures of cis-palladium(II) and cis-platinum(II) complexes containing dipyridyl ligands

Spectroscopic, structure and DFT studies of palladium(II) complexes with pyridine-type ligands

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