Citalopram for compulsive shopping disorder: A double-blind study

Koran, Lorrin M.; Chuong, H W; Bullock, Kim; Smith, S. A. de

doi:10.1016/s0924-977x(02)80707-6

Cited by 35 publications

(56 citation statements)

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“…Double-blind, placebo-controlled trials should be conducted to test the relative effectiveness of various medications, particularly serotonergically active drugs that have been shown to be effective in other disorders of impulse control. [18][19][20] Drug names: buspirone (BuSpar and others), escitalopram (Lexapro), fluoxetine (Prozac and others), lithium (Lithobid, Eskalith, and others), naltrexone (Revia and others), sertraline (Zoloft), topiramate (Topamax), trazodone (Desyrel and others), valproic acid (Depakene and others).…”

Section: Resultsmentioning

confidence: 99%

“…9,[14][15][16][17] Given the success in double-blind placebo-controlled trials of selective serotonin reuptake inhibitors (SSRIs) in the treatment of other impulse control disorders, [18][19][20] it is plausible that kleptomania may be similarly responsive. We are currently conducting the first double-blind placebo-controlled trial to test this hypothesis, using the SSRI escitalopram.…”

Section: Discussionmentioning

confidence: 99%

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Overview of Kleptomania and Phenomenological Description of 40 Patients

Aboujaoude¹,

Gamel²,

Koran³

2004

Prim. Care Companion CNS Disord.

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Background: Despite its considerable personal toll and its impact on the economy and the legal system, kleptomania is an understudied psychiatric disorder. Method:We review what is known about the epidemiology, course, and treatment of kleptomania and describe 40 patients meeting DSM-IV criteria for the disorder.Results: Our data suggest a female preponderance, with an early age at onset and most often a continuous course. No other gender-based differences were seen. The majority of our subjects had not received treatment for kleptomania despite often having sought help for comorbid psychiatric conditions, most commonly major depressive disorder. Our data confirm kleptomania's devastating effects on personal and professional lives and serious legal consequences, reflected in high arrest and incarceration rates. Because patients with kleptomania rarely seek psychiatric help for the disorder, we indicate how other health care providers can screen for it, possibly as part of taking patients' legal and social histories, and suggest treatments.Conclusion: Awareness of kleptomania, empathy toward those afflicted, and rigorous research into treatment options are needed to mitigate kleptomania's personal and societal costs.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Overview of Kleptomania and Phenomenological Description of 40 Patients

Aboujaoude¹,

Gamel²,

Koran³

2004

Prim. Care Companion CNS Disord.

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“…Despite the high prevalence and the detrimental impact for both, the individual and the society, studies investigating single facets of pathological buying such as neuropsychological or neurobiological correlates are scarce so far. The serotonergic, dopaminergic and opioide systems may be involved in the aetiology and pathogenesis of pathological buying (Grant, 2003;Koran, Aboujaoude, Solvason, Gamel & Smith, 2007;Koran, Chuong, Bullock & Smith, 2003). On a neural level, one assumes dysfunctions in cognitive (dorsolateral prefrontal cortex, nucleus caudatus) and affective brain circuits (ventromedial prefrontal/orbitofrontal cortex, nucleus accumbens, anterior cingulate cortex, basolateral amygdala) (review in Black, 2007).…”

Section: Introductionmentioning

confidence: 99%

Cue reactivity towards shopping cues in female participants

Starcke¹,

Schlereth²,

Domass³

et al. 2013

Journal of Behavioral Addictions

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Background and aims: It is currently under debate whether pathological buying can be considered as a behavioural addiction. Addictions have often been investigated with cue-reactivity paradigms to assess subjective, physiological and neural craving reactions. The current study aims at testing whether cue reactivity towards shopping cues is related to pathological buying tendencies. Methods: A sample of 66 non-clinical female participants rated shopping related pictures concerning valence, arousal, and subjective craving. In a subgroup of 26 participants, electrodermal reactions towards those pictures were additionally assessed. Furthermore, all participants were screened concerning pathological buying tendencies and baseline craving for shopping. Results: Results indicate a relationship between the subjective ratings of the shopping cues and pathological buying tendencies, even if baseline craving for shopping was controlled for. Electrodermal reactions were partly related to the subjective ratings of the cues. Conclusions: Cue reactivity may be a potential correlate of pathological buying tendencies. Thus, pathological buying may be accompanied by craving reactions towards shopping cues. Results support the assumption that pathological buying can be considered as a behavioural addiction. From a methodological point of view, results support the view that the cue-reactivity paradigm is suited for the investigation of craving reactions in pathological buying and future studies should implement this paradigm in clinical samples.

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“…Although a role has been suggested for opiate, serotonergic, and dopaminergic systems dysfunctions in this condition, the precise alterations in these neurotransmitters are still unclear [6]. For instance, the evidence supporting the utility of serotonin reuptake inhibitors in compulsive buying is mixed, i.e., while citalopram has shown some benefit [13], escitalopram [14] and fluvoxamine did not [15,16]. One additional concern is that the number of different buying behaviors required to qualify compulsive buying as potentially addictive, is unclear [17].…”

Section: Compulsive Buyingmentioning

confidence: 99%

DSM-5 and the Decision Not to Include Sex, Shopping or Stealing as Addictions

et al. 2014

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For the first time substance use will not be required for the diagnosis of addiction in diagnostic classification manuals, such as DSM and ICD. The DSM-5 has included gambling disorder, along with substance use disorders, as forms of addictions in a new chapter named "Substancerelated and addictive disorders", thus reflecting evidence that gambling behaviors activate reward systems similarly to drugs of abuse. However, there is still debate on whether other less recognized forms of impulsive behaviors, such as compulsive buying (oniomania), compulsive sex, and kleptomania can be conceptualized as addictions. In this review, we critically evaluate the literature on these behaviors with a focus on socio-demographic and clinical characteristics, underlying neurobiology and treatment response, and their potential overlap with substance use disorders. We were unable to find a substantial number of studies supporting a relationship of the aforementioned reward-based conditions to substance use disorders, thus supporting the contention not to include compulsive buying, compulsive sex, and kleptomania in DSM-5 as behavioral addictions.

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Citalopram for compulsive shopping disorder: A double-blind study

Cited by 35 publications

References 0 publications

Overview of Kleptomania and Phenomenological Description of 40 Patients

Overview of Kleptomania and Phenomenological Description of 40 Patients

Cue reactivity towards shopping cues in female participants

DSM-5 and the Decision Not to Include Sex, Shopping or Stealing as Addictions

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