Citronella oil‐loaded electrospun micro/nanofibrous matrices as sustained repellency systems for the Asian tiger mosquitoAedes albopictus

Abstract

BACKGROUND: Mosquitoes are hematophagous insects of major public health concern, serving as vectors of many diseases. Available products for personal protection against mosquitoes lack adequate efficacy and in most cases need to be reapplied or replaced frequently. In recent years, the encapsulation of the active repellents in various matrices has arisen as an alternative method for the development of new-generation repellent systems. The aim of the present study was to explore the potential of functional micro/nanofibrous matrices as systems for the sustained release of the highly volatile insect-repellent citronella oil. RESULTS: Micro/nanofibrous single-and triple-layer systems incorporating citronella oil as the active agent were developed via the electrospinning technique using the low-cost, non-toxic, biodegradable polymers cellulose acetate and polyvinylpyrrolidone. All the micro/nanofiber systems produced exhibited prolonged release of citronella oil and a high repellent activity in laboratory bioassays against the mosquito Aedes albopictus for at least 4 weeks. CONCLUSION: Considering the high volatility of the embedded repellent, the present study demonstrates the strong potential of the micro/nanofibrous matrices to act as carriers of highly volatile repellents for an effective and sustained protection from mosquitoes. Gas chromatography-mass spectrometryGC-MS analyses were conducted using an Agilent Technologies 7820A gas chromatograph equipped with a HP-5MS capillary column (30 m × 0.25 mm, film thickness 0.25 m), an Agilent Technologies 5977B MS detector operating in electron ionization mode at 70 eV and an Agilent Technologies 7693A automatic liquid sampler. Injection was performed at 280 ∘ C in a split ratio Pest Manag Sci 2019; 75: 2142-2147

Si̇vri̇si̇nek Kovucu Teksti̇l Malzemeleri̇ Üzeri̇ne Bi̇r Derleme

“…Çevresel kaygılarla birlikte bazı sivrisineklerin mevcut sentetik kovuculara dirençli hale gelmesi sentetik kovucuların etkili kullanımlarını engellemiştir [29]. Son yıllarda, insan kullanımı için daha güvenli ve çevre dostu oldukları düşünüldüğünden, doğal kovuculara olan ilgi artmıştır [2].…”

“…Iliou ve ark. [2], sivrisinek kovucu ajan olarak sitronella yağı içeren selüloz asetat ve polivinilpirolidon (PVP) bazlı tek ve üç katmanlı elektro çekilmiş yüzeyler üretmişlerdir. Polimer çözeltilerine %5 ve %20 olmak üzere iki konsantrasyonda sitronella yağı ilave edilerek karışım elektro çekim çözeltileri hazırlanmıştır.…”

“…Kapsülleme yöntemleri, uçucu yağın aktif bileşenlerinin kademeli ve kontrollü salınımını sağlarken etkinlik süresini artırmaktadır. Böylece, kovucuların ciltle doğrudan temas etmesi önlenirken; lifli yapıların yüksek spesifik yüzey alanları sayesinde maksimum iticilik sağlayan optimum buharlaşma kapasitesi elde edilebilmektedir [2][3][4][5]. Bugüne kadar çeşitli uçucu yağların kapsüllenerek tekstil yüzeylerine emdirilmesi yönünde çok sayıda çalışma yapılmıştır.…”

Functionalized biomaterials based on poly(vinyl alcohol) and chitosan as a vehicle for controlled release of cabreuva essential oil

“…[23] On the other hand, an important property of films loaded with EOs is their capacity to act as a device of controlled release, which represents an advantage from the biomedical point of view. Although diverse works exist dedicated to the controlled release of EOs from polymer matrix, [24][25][26] there is no comprehensive evaluation of the kinetics of the release process. In this regard, the understanding of the mechanism involved in the delivery of an active compound and its relationship with the composition and the stability of the matrix are aspects to be considered when designing tailor-made materials that act as controlled release supports.…”

Citronella Oil Nanoemulsion: Formulation, Characterization, Antibacterial Activity, and Cytotoxicity

“…For instance, citronella oil, a natural plant essential oil belonging to the genus Citronella of Gramineae, is obtained from the Cymbopogon nardus through steam distillation 10 . Citronella oil is regarded as an insect repellent 11 and is effective in refreshing the mind, purifying the room, and softening the skin 12 . Moreover, it can be used in cleaning oily skin and sweaty feet 13 .…”