Citrus limetta peels derived carbon dots as highly active carbocatalyst for carbon–carbon bond formation

Chugh, Riya; Kaur, Gurmeet

doi:10.1007/s10098-023-02657-2

Cited by 1 publication

(1 citation statement)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…12 Further, Gao et al have synthesized CDs at a temperature of 180 °C for 5 h. 13 In another study, He and his team have synthesized citric acid and nitric acid based CDs in a two-step process at a temperature range of 170−250 °C for 1−5 h. 14 Later on, Farzaneh and Chugh in two different studies synthesized CDs at temperatures greater than 200 and 150 °C. 15,16 To encounter this challenge, there is an urgent need to look for one-step CD synthesis approaches so that they can be easily translated to the semipilot/pilot scale for their biomedical applications, such as probes in diverse biological models. The use of a relatively lower temperature can be explained by its role in facilitating the carbonization of citric acid and ascorbic acid.…”

Section: Introductionmentioning

confidence: 99%

Single-Step Low-Temperature Synthesis of Carbon Dots for Advanced Multiparametric Bioimaging Probe Applications

Ghosh,

Gautam,

Gupta

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

Carbon dots (CDs) have recently emerged in biomedical and agricultural domains, mainly for their probe applications in developing efficient sensors. However, the existing high-temperature approaches limit the industrial level scaling up to further translate them into different products by mass-scale fabrication of CDs. To address this, we have attempted to lower the synthesis temperature to 140 °C and synthesized different CDs using different organic acids and their combinations in a one-step approach (quantum yield 3.6% to 16.5%; average size 3 to 5 nm). Further, sensing applications of CDs have been explored in three different biological models, mainly Danio rerio (zebrafish) embryos, bacterial strains, and the Lactuca sativa (lettuce) plant. The 72 h exposure of D. rerio embryos to 0.5 and 1 mg/mL concentrations of CDs exhibited significant uptake without mortality, a 100% hatching rate, and nonsignificant alterations in heart rate. Bacterial bioimaging experiments revealed CD compatibility with Gram-positive (Bacillus subtilis) and Gram-negative (Serratia marcescens) strains without bactericidal effects. Furthermore, CDs demonstrated effective conduction and fluorescence within the vascular system of lettuce plants, indicating their potential as in vivo probes for plant tissues. The single-step low-temperature CD synthesis approach with efficient structural and optical properties enables the process as industrially viable to up-scale the technology readiness level. The bioimaging of CDs in different biological models indicates the possibility of developing a CD probe for diverse biosensing roles in diseases, metabolism, microbial contamination sensing, and more.

show abstract