Classic Hodgkin Lymphoma: A Nonclassic Presentation

Abstract

Hodgkin lymphoma classically presents as lymphadenopathy with contiguous spread with or without associated B symptoms including night sweats, weight loss, and fever. With timely diagnosis and treatment, this is a potentially curable disease. This report describes a unique case of Hodgkin lymphoma that presented with localized back pain without overt evidence of lymph node involvement. This nonclassic presentation offers a diagnostic challenge that emphasizes the importance of keeping a broad differential in an adolescent or young adult patient with lytic bone lesions.

A Rare First Presentation of Hodgkin's Lymphoma: Symptomatic Pericardial Effusion

“…Regarding HL, patients can also present with lymphadenopathy, hepatic and spleen enlargement, and pruritus [14,15]. However, in the literature, there are some reports of atypical and rare first clinical presentations, such as the one we describe here [4,6,[16][17][18]. In fact, pericardial effusion is a rare finding, accounting for about 5-6% of the patients diagnosed with HL.…”