Classification and approach to bronchiolar diseases

Ryu, Jay H.

doi:10.1097/01.mcp.0000208455.80725.2a

Cited by 86 publications

(63 citation statements)

References 54 publications

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“…(Mohr, 2004;Ohtani et al, 2005;Churg et al, 2006). Also fibrosis may be seen in the peri-bronchiole areas and in some cases bronchiolitis obliterans may be present (Mohr, 2004;Ohtani et al, 2005;Churg et al, 2006;Ryu, 2006).…”

Section: Hypersensitivity Pneumonitismentioning

confidence: 99%

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Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

et al. 2007

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Pulmonary fibrosis is a general term that refers to a collection of connective tissue around alveolar structures. There are over 200 disorders where the lungs may be involved in a fibrotic response. To determine the cause of pulmonary fibrosis requires an in depth understanding of the pathogenesis of pulmonary fibrosis and breadth of knowledge of the causative agents and associated disorders that may lead to pulmonary fibrosis. A comprehensive evaluation of the patient is absolutely essential, starting with detailed history that includes an occupational and environmental history because fibrogenic exposures can occur in many settings. Equally important is a history of ingestion of pharmaceutical or nonpharmaceutical substances. A physical examination and judicious investigations are always a part of any comprehensive clinical assessment but they are not commonly helpful in elucidating the cause of most pulmonary fibrotic disorders. Although, a chest film is invariably done, a logical and strongly recommended next step is a high-resolution computed tomography (HRCT). HRCT provides a better assessment of the radiological pattern, may suggest a diagnosis as well as direct the site, and type of lung biopsy. If the history and investigations do not lead to a diagnosis then a lung biopsy is required. Prevention or removal of the inciting agent is critical to the treatment of these disorders and in some instances corticosteroids may be of help.

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Section: Hypersensitivity Pneumonitismentioning

confidence: 99%

“…However, other histological patterns such as bronchiolitis obliterans with organizing pneumonitis (BOOP) may be seen as many as 50% of HP/EA cases (Mohr, 2004;Ryu, 2006). When BOOP is FIGURE 1.-(A) Histology of hypersensitivity pneumonitis.…”

Section: Hypersensitivity Pneumonitismentioning

confidence: 99%

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

et al. 2007

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“…(130) Figure 26 -High-resolution computed tomography scan demonstrating a combination of patchy groundglass opacity and air trapping in the same patient. This is termed the "headcheese" or "terrine" sign and is highly suggestive of hypersensitivity pneumonitis.…”

Section: Constrictive Bronchiolitismentioning

confidence: 99%

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

et al. 2008

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High-resolution computed tomography (HRCT) is the radiological imaging technique best suited to revealing changes in lung structure. Various HRCT findings, taken together, can represent typical patterns. These patterns, in conjunction with the anatomical distribution of findings and with clinical data, can narrow the differential diagnosis of diffuse interstitial lung disease and, in many cases, indicate the correct diagnosis with a high degree of accuracy. The most common HRCT patterns seen in cases of diffuse interstitial lung diseases are the nodular pattern, linear/reticular opacities, cystic lesions, ground-glass opacities and consolidations. This article reviews the correlations between HRCT patterns and pathologic findings, summarizing the most common causes, as well as detailing the methods of investigation employed in order to diagnose the most common types of chronic diffuse lung disease.Keywords: Lung diseases, interstitial/pathology; Tomography, X-Ray computed; Diagnostic techniques, respiratory system. ResumoA tomografia de alta resolução (TCAR) é a técnica de imagem radiológica que reflete mais de perto as alterações da estrutura pulmonar. Os vários achados tomográficos podem ser combinados para formar padrões típicos. Estes, conjuntamente com a distribuição anatômica dos achados, e com os dados clínicos, podem estreitar o diagnóstico das doenças intersticiais pulmonares difusas, e em vários casos sugerir o diagnóstico correto com alto grau de acurácia. Os padrões mais comuns das doenças intersticiais pulmonares difusas na TCAR são o nodular, linear e reticular, lesões císticas, opacidades em vidro fosco e consolidações. Este artigo revisa as correlações entre os padrões tomográficos na TCAR e os achados patológicos e resume as causas mais comuns e os métodos de investigação para se atingir um diagnóstico nas doenças pulmonares crônicas difusas mais comuns.Descritores: Doenças pulmonares intersticiais/patologia; Tomografia computadorizada por raios X; Técnicas de diagnóstico do sistema respiratório.* Study carried out in the

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“…Desde el punto de vista anatómico, las diferentes entidades clínicas se manifi estan por cambios infl amatorios de magnitud variable y morfología distintiva centrados en la vía aérea pequeña, constituida por los bronquiolos menores de 2 mm de diámetro que no contienen tejido cartilaginoso de sostén en su pared [3][4][5] . La bronquiolitis puede presentarse en diversos escenarios clínicos, como enfermedad primaria (bronquiolitis obliterante, por exposición a polvos minerales o gases irritantes, infección viral, etc), como parte de una enfermedad intersticial (neumonitis por hipersensibilidad, bronquiolitis respiratoria del fumador o RB-ILD, enfermedad colágeno-vascular) o en el contexto de una enfermedad de la vía aérea de mayor calibre, como sucede en pacientes portadores de asma bronquial, fi brosis quística, enfermedad pulmonar obstructiva crónica o bronquiectasias 1,[3][4][5][6][7] .…”

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Evaluación clínico-radiológica y clasificación de la bronquiolitis del adulto

et al. 2011

Rev. méd. Chile

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puc.cl L a enfermedad bronquiolar o bronquiolitis corresponde a un proceso inespecífi co, infl amatorio o fi brótico, de múltiples orígenes que involucra a los bronquiolos y alvéolos, se manifi esta por síntomas respiratorios inespecífi cos y compromiso funcional variable, que difi eren en su evolución, gravedad y pronóstico [1][2][3] . Desde el punto de vista anatómico, las diferentes entidades clínicas se manifi estan por cambios infl amatorios de magnitud variable y morfología distintiva centrados en la vía aérea pequeña, constituida por los bronquiolos menores de 2 mm de diámetro que no contienen tejido cartilaginoso de sostén en su pared 3-5 . La bronquiolitis puede presentarse en diversos escenarios clínicos, como enfermedad primaria (bronquiolitis obliterante, por exposición a polvos minerales o gases irritantes, infección viral, etc), como parte de una enfermedad intersticial (neumonitis por hipersensibilidad, bronquiolitis

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Classification and approach to bronchiolar diseases

Cited by 86 publications

References 54 publications

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

Environmental, Inhaled and Ingested Causes of Pulmonary Fibrosis

Padrões tomográficos das doenças intersticiais pulmonares difusas com correlação clínica e patológica

Evaluación clínico-radiológica y clasificación de la bronquiolitis del adulto

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