“…Especially, algorithms for the delineation of anatomical structures and other regions of interest are a key component in assisting and automating specific radiological tasks. These algorithms, named image segmentation algorithms, play a fundamental role in many medical imaging applications such as the quantification of tissue volumes [3,4], diagnosis [5], localization of pathology [6,7], study of anatomical structure [8,9], treatment planning [10], partial volume correction of functional imaging data [11], and computer integrated surgery [12][13][14]. Techniques for carrying out segmentations vary broadly depending on some factors such as specific application, imaging modality, etc.…”