“…Also, PLR responses based on Melanopsin ganglion cells [15,21,40] can be applied to the study of Aged Macular Disease (AMD) and AD [15,21,8], and the possibility of their use in diagnosing these diseases has been studied [29,34,32,31]. A simple procedure to detect AMD and AD patients is required for medical and clinical staff who treat elderly people [33]. In a sense, a diagnostic procedure using ocular-motors may be an easy method, as it does not require verbal communication.…”