“…For example, in medical diagnosis, misclassifying a malignant tumor biopsy sample as benign is more severe than misclassifying a benign sample as malignant (Mazurowski et al, 2008, Park et al, 2011, Moon et al, 2012; in email spam detection, removing a non-spam email leads to more severe consequences than missing a spam email (Carreras andMarquez, 2001, Zhou et al, 2014); in political conflict prediction, missing a conflict has more critical consequences than vice versa (Beck et al, 2000, Cederman andWeidmann, 2017). In addition to these examples, asymmetric binary classification problems exist in geologic studies (Horrocks et al, 2015, Fernández-Gómez et al, 2017, fraud detection (Sahin et al, 2013, Bahnsen et al, 2013, and other medical diagnosis and prognosis problems (Artan et al, 2010, Ali et al, 2016.…”