Clathrin-mediated endocytosis: the gateway into plant cells

A Membrane Microdomain-Associated Protein, Arabidopsis Flot1, Is Involved in a Clathrin-Independent Endocytic Pathway and Is Required for Seedling Development

“…Apart from the well-studied clathrin-dependent endocytosis (Chen et al, 2011), other entry pathways, including membrane raftmediated endocytosis, also operate in plant cells (Murphy et al, 2005;Moscatelli et al, 2007;Bandmann and Homann, 2011). Recent studies suggested that plant flotillins play a critical role in symbiotic bacterial infection of M. truncatula (Haney and Long, 2010;Haney et al, 2011), and the recycling of PIN proteins may depend on structural sterols and membrane rafts in Arabidopsis Willemsen et al, 2003;Men et al, 2008).…”

“…This process plays a central role in the maintenance of the protein and lipid composition within the plasma membrane; endocytosis also mediates in the removal or recycling of materials from the apoplasm or extracellular space (Conner and Schmid, 2003;Dhonukshe et al, 2008;Tanaka et al, 2009;Chen et al, 2011).…”

Adaptor Protein Complex 2–Mediated Endocytosis Is Crucial for Male Reproductive Organ Development in Arabidopsis

“…However, current knowledge indicates that endocytosis occurs via multiple routes with or without clathrin and plays a pivotal role in various essential cellular processes, such as cell signaling, cell fate determination, cell division, and cell mobility, thus being considered a major player in the regulation of cellular signaling circuits (Fischer et al, 2006;Chen et al, 2011;Andersson, 2012). The underlying principle by which endocytosis plays a role in these processes is to orchestrate spatially and temporally the level and type of proteins localized at the PM and endosomes according to the cellular environment (Polo and Di Fiore, 2006;Sigismund et al, 2012).…”

“…In contrast with the vast knowledge on the role of endocytosis in various cellular processes in animal cells, only recently has it become clear that endocytosis plays a similar crucial role in plants (Friml, 2010;Chen et al, 2011). The physiological importance of endocytosis in plants has been demonstrated by the polar distribution of PINs and boron transporters in root cells, which are mediated by endocytosis (Takano et al, 2005;Dhonukshe et al, 2007;Friml, 2010;Grunewald and Friml, 2010).…”

Endocytic Accessory Factors and Regulation of Clathrin-Mediated Endocytosis

“…R eceptor-mediated endocytosis is the process by which eukaryotic cells concentrate and internalize cell surface receptors from the plasma membrane into small ( 50 nm-100 nm diameter) membrane vesicles (Chen et al 2011;McMahon and Boucrot 2011;Weinberg and Drubin 2012). This mechanism has been studied extensively in mammalian tissue culture cells and in yeast, and despite the evolutionary distance between yeast and mammalian cells the mechanism of receptor-mediated endocytosis in the respective cell types show remarkable similarities.…”