Clean and efficient synthesis of 3-aminoindolizines in one-pot using recyclable CuCN/[bmim]PF ₆ system

Recent advances in the application of alkynes in multicomponent reactions

“…Mohammod and co-workers 81 synthesized 3-aminoindolysines 170 via the reaction among pyridine-2-carbaldehyde 167, secondary amine derivatives 168, and terminal alkyne derivatives 169 in the presence of the CuCN/[bmim][PF 6 ] system under an N 2 atmosphere at 70 °C ( Scheme 72 ).…”