Nuclear power, as a low-carbon, stable, and efficient energy, plays an important role in replacing fossil fuels in the development of a globally sustainable energy system. However, nuclear power has deviated from the path to achieve the Sustainable Development Goals of the United Nations. The path of sustainable nuclear power for China was proposed based on an analysis of the development of global nuclear power and the situation in China, using advanced operation concepts and intelligent collaboration technology to change the labor-centered operation mode. It serves as a model for other countries with a labor-centered nuclear power operation mode and an aging society seeking to achieve carbon neutrality through the use of nuclear power around the world.