Clear cell carcinoma of the seminal vesicle in a young adult

Abstract

Introduction Most seminal vesicle malignancies are secondary to prostate or bladder cancer. Herein, we report a case of primary clear cell carcinoma of the seminal vesicle. Case presentation A 27‐year‐old man was referred to our department for hematospermia and macroscopic hematuria. A digital rectal examination showed a soft elastic prostatic mass. Cystoscopy showed no bladder abnormalities, and tumor marker tests were unremarkable. Contrast‐enhanced computed tomography and magnetic resonance imaging revealed a cystic tumor containing an enhanced nodule near the prostate and seminal vesicle. The tumor was removed en bloc with the prostate and seminal vesicle through a laparoscopic radical prostatectomy. A histopathologic examination confirmed the diagnosis, with the tumor likely arising from a remnant Müllerian epithelium. A 1‐year follow‐up revealed local tumor recurrence, prompting laparoscopy. Conclusion A standard therapy for primary seminal vesicle carcinoma has not been established. Further studies are necessary to determine the optimal treatment strategy.

Primary Mullerian‐type clear cell carcinoma of the seminal vesicle presenting as a testicular mass

“…3 Two additional cases have been reported possibly arising in Mullerian rests/cysts within the pelvis, adjacent to seminal vesicles. 4,5 Herein we report a primary Mullerian-type clear cell carcinoma of the seminal vesicle with supportive immunohistochemical reactivity and a unique clinical presentation.…”