Clear Cell Carcinoma of the Male Urethra Presenting as Periurethral Abscess With Fistulae

Varachhia, Saleem; Goetz, Lester; Persad, Rajendra; Naraynsingh, Vijay

doi:10.1097/spv.0b013e3181b12373

Cited by 3 publications

(1 citation statement)

References 3 publications

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“…Most described clinical manifestations of this malignant neoplasia include hematuria, obstructive symptoms, urinary retention, and recurrent urinary tract infections. 9,10 However, in two clinical cases reports the clinical presentation was periurethral abscess and fistula, 11 and chronic symptoms related to urethral trauma from a vehicle accident. 9 In the case described above, the patient remained oligosymptomatic until diagnosis and subsequent surgery.…”

Section: Discussionmentioning

confidence: 99%

Clear cell adenocarcinoma of the male urethra: clinical case report

Santos¹,

Mendes²,

Monteiro³

2021

Brazilian Journal of Oncology

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O adenocarcinoma de células claras primário da uretra é uma doença maligna rara e a maioria dos casos descritos são em mulheres. A sintomatologia é semelhante a outros tumores da uretra. Por se tratar de uma neoplasia rara e a consequente falta de ensaios na literatura médica, não existem dados sobre o tratamento mais adequado para esta doença. Nosso objetivo é descrever um caso clínico de adenocarcinoma de células claras primário da uretra em um paciente jovem do sexo masculino. Trata-se de um homem de 36 anos com diagnóstico de adenocarcinoma de células claras primário da uretra que foi submetido a uma cirurgia para doença localizada e cerca de 30 meses depois apresentou recorrência local e sistêmica. Foi tratado com quimioterapia à base de platina e apresentou excelente resposta clínica e radiológica. Embora não haja um tratamento ideal para essa malignidade, no caso de doença metastática, a quimioterapia sistêmica à base de platina deve ser considerada uma opção apropriada.

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Section: Discussionmentioning

confidence: 99%

Clear cell adenocarcinoma of the male urethra: clinical case report

Santos¹,

Mendes²,

Monteiro³

2021

Brazilian Journal of Oncology

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Clear cell adenocarcinoma of the male urethra: a case report

et al. 2022

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Background Primary urethral cancer in males is rare. Clear cell adenocarcinoma is more rare. We report a case in an African male suspected to have a urethral stricture. Case presentation A 66-year-old man presented in with preceding intermittent haematuria and acute urinary retention. Failed attempts at catheterisation necessitating a suprapubic catheter insertion raised the suspicion of a urethral stricture. Multiple irregular urethral filling defects were seen on a retrograde urethrogram. Urethroscopy revealed obstructing urethral masses. Histology reported clear cell adenocarcinoma. Conclusion Primary urethral cancer should be entertained as a differential diagnosis of a urethral stricture in a patient with haematuria, difficult urethral catheterisation and ambiguous urethrogram findings. Cystoscopy and biopsy are essential in the investigative work-up to make the distinction.

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