Clearance of lung metastases of breast carcinoma after treatment with triptorelin in postmenopausal woman

Sánchez-Garrido, F; Comaru-Schally, A. M.; Cura, G. Sanchez del; Gonzales-Enriquez, J.; Schally, A. V.

doi:10.1016/s0140-6736(95)93009-4

The Lancet

1995

DOI: 10.1016/s0140-6736(95)93009-4

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Clearance of lung metastases of breast carcinoma after treatment with triptorelin in postmenopausal woman

F Sánchez-Garrido¹,

A. M. Comaru-Schally²,

G. Sanchez del Cura³

et al.

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Cited by 2 publications

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Menopause LiteratureWatch

1995

Journal of Women's Health

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treatment and endometrial pathology. Obstet Gynecol Surv 1994 Dec;49(12):823-829. Collichio F, Pandya K. Amenorrhea following chemotherapy for breast cancer: Effect on disease-free survival. Oncology (Huntingt) 1994 Dec;8(12):45-52. Gow SM, Turner EI, Glasier A. The clinical biochemistry of the menopause and hormone replacement therapy. Ann Clin Biochem 1994 Nov;31(6):509-528. Lanza A, Alba E, Re A, Tessarolo M, Leo L, Bellino R, Lauricella A, Wierdis T. Endometrial carcinoma in breast cancer patients treated with tamoxifen; Two case reports and review of the literature. Eur J Gynaecol Oncol 1994;15(6):45S459. Saminathan T, Lahoti C, Kannan V, Kline TS. Postmenopausal squamous-cell atypias: A diagnostic challenge. Diagn Cytopathol 1994;ll(3):226-230. Spiegel GW. Endometrial carcinoma in situ in postmenopausal women. Am J Surg Articles The importance of sexual rehabilitation after breast cancer treatment. Oncology (Huntingt) 1994 Dec;8(12):15-16.Algotsson A, Nordberg A, Winblad B. Influence of age and gender on skin vessel reactivity to endothelium-dependent and endothelium-independent vasodilators tested with iontophoresis and a laser Doppler perfusion imager. The influence of menopause and hormonal replacement therapy on body cell mass and body fat mass. Am J Obstet Gynecol 1995 Mar;172(3):896-900. Armamento-Villareal R, Civitelli R. Estrogen action on the bone mass of postmenopausal women is dependent on body mass and initial bone density.

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1995

Journal of Women's Health

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Spotlight on triptorelin in the treatment of premenopausal women with early-stage breast cancer

Venturelli

Guaitoli

Omarini

et al. 2018

BCTT

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Endocrine treatment represents the cornerstone of endocrine-sensitive premenopausal early breast cancer. The estrogen blockade plays a leading role in the therapeutic management of hormone receptor-positive breast cancer together with surgery, radiotherapy, and selective antiestrogen treatments. For several years, selective estrogen receptor modulators, such as tamoxifen, have represented the mainstay of therapy. The role of amenorrhea has been extensively elucidated in the past year: the benefit observed with chemotherapy-induced amenorrhea has strengthened its therapeutic role. Luteinizing hormone-releasing hormone (LHRH) has been introduced in oncology practice to induce amenorrhea in order to increase the advantage obtained from endocrine treatment. Triptorelin is one of the most widely used LHRH analogs currently available in clinical practice. It was recently investigated in two major clinical trials that studied the role of complete estrogen blockade in the premenopausal setting. Both showed the clinical benefit due to ovarian suppression treatment, primarily in high-risk patients. Furthermore, triptorelin and other LHRH analogs have recently been investigated in the attempt to preserve the ovarian function in young patients. The medical treatment of early breast cancer is always evolving in the effort to search for safe and efficacious treatments. The role of LHRH analogs is actually well recognized as contributing to the improvement of the medical treatment of premenopausal women with early breast cancer.

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Clearance of lung metastases of breast carcinoma after treatment with triptorelin in postmenopausal woman

Cited by 2 publications

References 3 publications

Menopause LiteratureWatch

Menopause LiteratureWatch

Spotlight on triptorelin in the treatment of premenopausal women with early-stage breast cancer

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