2020
DOI: 10.1177/0300060520945502
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Clearing heat and resolving phlegm for acute exacerbation of chronic obstructive pulmonary disease with the syndrome of phlegm-heat obstruction of the lung

Abstract: Objective This study aimed to evaluate the effect of clearing heat and resolving phlegm for acute exacerbation of chronic obstructive pulmonary disease with the syndrome of phlegm-heat obstruction of the lung. Methods This was a real-world retrospective cohort study of inpatients at our institution from 1 January 2015 to 31 December 2017. The patients were divided into two groups according to whether they received oral traditional Chinese medicine (TCM) for clearing heat and resolving phlegm or routine treatme… Show more

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Cited by 3 publications
(6 citation statements)
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References 28 publications
(70 reference statements)
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“…In total, 23 RCTs ( 36 , 37 , 47 , 53 , 60 , 61 , 63 , 64 , 68 , 70 , 72 , 74 , 75 , 77 , 79 - 82 , 84 - 88 ) involving 4 CHIs were used to analyze the change in PCT. Patients receiving TRQ + WM showed significant improvement in PCT compared to those who received WM alone or XBJ + WM, with MD and 95% CIs of −2.40 (−3.48 to −1.32) and −1.74 (−3.46 to −0.01), respectively ( Table S1 ).…”
Section: Resultsmentioning
confidence: 99%
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“…In total, 23 RCTs ( 36 , 37 , 47 , 53 , 60 , 61 , 63 , 64 , 68 , 70 , 72 , 74 , 75 , 77 , 79 - 82 , 84 - 88 ) involving 4 CHIs were used to analyze the change in PCT. Patients receiving TRQ + WM showed significant improvement in PCT compared to those who received WM alone or XBJ + WM, with MD and 95% CIs of −2.40 (−3.48 to −1.32) and −1.74 (−3.46 to −0.01), respectively ( Table S1 ).…”
Section: Resultsmentioning
confidence: 99%
“…A total of 31 RCTs involving 4 CHIs were used to analyze the change in the WBC [2015–2022, 15 studies ( 34 , 35 , 37 , 38 , 58 - 61 , 67 - 70 , 74 , 77 , 79 ); 2006–2014, 16 studies ( 22 , 25 , 26 , 29 , 33 , 41 , 44 , 45 , 49 , 53 , 89 - 94 )]. XYP + WM, XBJ + WM, TRQ + WM, and RDN + WM had a significant effect on WBC compared to WM regimen alone, with MD and 95% CIs of −1.92 (−3.64 to −0.20), −1.50 (−1.89 to −1.12), 0.88 (0.47 to 1.29), and 1.95 (1.14 to 2.76), respectively ( Table S2 ).…”
Section: Resultsmentioning
confidence: 99%
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“…It has been widely used for disease diagnosis (Wang et al, 2013), differential diagnosis (Deja et al, 2014), and therapeutic interventions (Ren et al, 2016). Several studies have explored biomarkers and pathophysiological mechanisms associated with the diagnosis and classification of TCM syndromes in AECOPD (Yang et al, 2018;Zhang et al, 2020). However, there is a lack of biomarker research on the efficacy of TCM syndromes.…”
Section: Introductionmentioning
confidence: 99%