Cleft Lip and Palate Treated by Presurgical Orthopedics, Gingivoperiosteoplasty, and Lip Adhesion (POPLA) Compared with Previous Lip Adhesion Method: A Preliminary Study of Serial Dental Casts

Predictors of poor dental arch relationship in young children with unilateral cleft lip and palate

“…Primary Millard's GPP was also associated with poor dental arch relationship. Although a number of studies have addressed the issue of Millard's GPP predisposition to poor maxillary growth, no clear conclusion has been reached as all the GPP patients also had active PSO [13][14][15][16][17]. Similarly, all the nonGPP patients did not have PSO.…”

“…One group found no difference in maxillary growth following GPP [11,12]. In contrast, others found poor maxillary growth in patients who had GPP [13][14][15][16][17]. However, it is impossible to clarify whether the growth disturbance was attributable to the active PSO or Millard's GPP.…”

Maxillary growth after maxillary protraction: Appliance in conjunction with presurgical orthopedics, gingivoperiosteoplasty, and Furlow palatoplasty for complete bilateral cleft lip and palate patients with protruded premaxilla

“…16e18 GPP is reportedly associated with bone formation; Santiago et al reported complete bone formation in 60%, 19 while Millard et al noted bone formation in 83.3% of BCLP patients treated with a Latham appliance and GPP. 8 However, many studies reported that the efficacy has been questioned or denied because there have been concerns over poor bone formation 20,21 and retardation of maxillary growth. 10e13 In this study, five of seven patients did not have sufficient bone formation to avoid ABG.…”

“…Adjusting the alignment of a protruding premaxilla by PSO has improved alveolar cleft shape, as well as lip and nose shape, 7 and promoted bone formation at the alveolar cleft through gingivoperiosteoplasty (GPP). 8 However, there have been concerns over retardation of maxillary growth and numerous studies have not reported any long-term benefits, 9e14 while subsequent palatoplasty potentially leads to additional retardation of maxillary growth. We have attempted to perform Furlow palatoplasty and maxillary protraction appliance (MPA) for postoperative retardation of maxillary growth cases.…”

Osteogenic potential of human umbilical cord-derived mesenchymal stromal cells cultured with umbilical cord blood-derived autoserum

“…In accordance with a published study (Millard et al, 1999), we have performed gingivoperiosteoplasty when required during cheiloplasty and have prepared the ground for osteogenesis. However, some paediatric patients have had difficulty undergoing orthodontic treatment in their school years or later because of the inadequate volume of bone tissue formed.…”