Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients

Jamilian, Abdolreza; Lucchese, Alessandra; Darnahal, Alireza; Kamali, Zinat; Perillo, Letizia

doi:10.1186/s40510-016-0127-z

Cited by 25 publications

(16 citation statements)

References 17 publications

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“…3). Our result here is divergent to widely reported higher left sided unilateral clefts than rightsided CLs [27][28][29]. Majority (40.4%) of CL/P were located bilaterally.…”

Section: Discussioncontrasting

confidence: 99%

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact

2019

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Background Cleft lip and palate deformities are considered one of the most common birth defects of the head and neck that pose significant medical, psychosocial and financial burdens on the affected individuals and families, especially in low income communities. The etiology and pathogenesis of cleft lip and palate is complex and is known to involve genetic and/or environmental factors. Objective To assess the patterns of anatomical cleft lip and palate deformities among neonates in Mekelle and Ayder Comprehensive Specialized hospitals, Tigray, Northern Ethiopia. Methods A hospital-based retrospective study was conducted from May 2017 to June 2017 at Mekelle and Ayder Comprehensive Specialized hospitals, both in Mekelle city. Data was collected from all medical charts of neonates registered from 2011 to 2016 and analyzed using SPSS version 21.0 and OpenEpi software. Results were presented using tables and graphs; Chi-square test was used to look for an association between variables, odds ratio to determine the strength of association of selected variables using multinomial logistic regression model, while Fisher Exact (Clopper-Pearson) was used to compare yearly prevalence. Results Of 37,152 neonatal charts analyzed, 119 (0.32%) cases were identified as having cleft deformities. 38.7, 17.6, and 43.7% of this figure had cleft lips, cleft palates and both cleft lip and palate respectively. 46 (38.7%) neonates had lateral patterns of cleft lip deformities with 56.5% located unilaterally on the right and 43.5% unilaterally on the left. Of 52 (43.7%) neonates with cleft lip and palate deformities, 40.4% were located bilaterally while 38.5 and 21.2% were located unilaterally on the left and right, respectively. Associated malformations were: cardiac (3.4%), central nervous system (1.7%) and limb deformities (5.9%). The overall prevalence of cleft deformities was found to be 3.11 per 1000 live births. Conclusion The study showed a higher prevalence of cleft deformities than that reported in Addis Ababa and some other African countries. A higher occurrence of left unilateral pattern of cleft lip and palate was observed whereas a higher right unilateral pattern of cleft lip was identified. The higher prevalence of cleft lip and palate recorded in this region of Ethiopia may reflect an environmental impact.

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“…3). Our result here is divergent to widely reported higher left sided unilateral clefts than rightsided CLs [27][28][29]. Majority (40.4%) of CL/P were located bilaterally.…”

Section: Discussioncontrasting

confidence: 99%

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact

2019

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“…Maxillary expansion is a widely used orthodontic technique that enables the correction of transversal upper-arch deficiency [1,2], a condition which can be related to both genetic and environmental factors [3]. Genetic factors [4] account for narrow developed maxilla and/or wide mandible and maxillary deficiencies in cases of cleft lip and palate patients [5,6]. Environmental factors are related to mouth breathing, which is often associated with posterior nasal obstruction and oral habits [7,8].…”

Section: Introductionmentioning

confidence: 99%

Midpalatal Suture Density Evaluation after Rapid and Slow Maxillary Expansion with a Low-Dose CT Protocol: A Retrospective Study

et al. 2020

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Background and objectives: The aim of the present paper is to use low-dose computed tomography (CT) to evaluate the changes in the midpalatal suture density in patients treated with rapid maxillary expansion (RME) and slow maxillary expansion (SME). Materials and Methods: Thirty patients (mean age 10.2 ± 1.2 years) were retrospectively selected from the existing sample of a previous study. For each patient, a low-dose computed tomography examination was performed before appliance placement (T0) and at the end of retention (T1), seven months later. Using the collected images, the midpalatal suture density was evaluated in six regions of interest. Results: No significant differences were found between the timepoints in the rapid maxillary expansion group. Three out of six regions of interest showed significant decreases between the timepoints in the slow maxillary expansion group. No significant differences were found in comparisons between the two groups. Conclusions: The midpalatal suture density showed no significant differences when rapid maxillary expansion groups were compared to slow maxillary expansion groups, suggesting that a similar rate of suture reorganization occurs despite different expansion protocols.

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“…Congenitally missing teeth is one of the most common anomalies observed in the maxillofacial region [ 1 – 6 ]. There are two main classifications of congenitally missing teeth: the syndromic type, phenotypically presenting as a syndrome of congenital disorders such as ectodermal dysplasia, and the non-syndromic type, which is simply a disorder characterized by multiple missing teeth [ 7 – 9 ]. The congenital absence of 1 to 5 teeth (excluding third molars) has been described as “hypodontia” by Schalk-van der Weide et al [ 10 ], while the absence of > 6 teeth is known as “oligodontia.” “Anodontia,” a very rare condition, is the absence of all teeth [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Examination of craniofacial morphology in Japanese patients with congenitally missing teeth: a cross-sectional study

et al. 2018

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BackgroundThe purpose of this cross-sectional study was to investigate the effects of congenitally missing teeth on craniofacial morphology and to characterize the features of maxillofacial morphology of oligodontia patients associated with individual skeletal maturity by assessment with the cervical vertebrae maturation (CVM) method.MethodsA total of 106 non-syndromic Japanese patients with congenitally missing teeth (except for third molars) were selected and categorized into two groups according to the severity of congenitally missing teeth (hypodontia group, 1–5 missing teeth [n = 56]; oligodontia group, ≥ 6 missing teeth [n = 50]). A control group included orthodontic patients without either skeletal disharmony or congenitally missing teeth (n = 63). Subjects in oligodontia and control groups were further categorized into two subgroups on the basis of cervical stage (CS): stage I (CS2 or 3; n = 27 and n = 31, respectively) and stage II (CS4 or above; n = 23 and n = 32, respectively). Lateral cephalograms were analyzed by using eight angular and eight linear measurements. Z-scores were formulated on the basis of age and sex and were matched to the Japanese norm. Tukey tests and t tests were performed.ResultsCompared with the control group, the hypodontia group had significantly smaller U1 to FH plane angle and A-B plane angle; U1-L1 was significantly larger. The oligodontia group had significantly smaller ANS-Me, L1 to mandibular plane angle, and Ptm-A; U1-L1 was significantly larger. At stage I, the oligodontia group had significantly smaller ANS-Me, gonial angle, and ANS-U1. At stage II, the oligodontia group had significantly smaller U1 to FH plane angle, L1 to mandibular plane angle, Ptm-A, and Go-Pog; it also had significantly larger U1-L1.ConclusionsThe present study suggested that skeletal patterns differ along with the number of congenitally missing teeth and that, in oligodontia patients, skeletal patterns differ before and after growth peak. It is important to consider the skeletal characteristics of tooth agenesis patients when designing a treatment plan.

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Cleft sidedness and congenitally missing teeth in patients with cleft lip and palate patients

Cited by 25 publications

References 17 publications

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact

Anatomical patterns of cleft lip and palate deformities among neonates in Mekelle, Tigray, Ethiopia; implication of environmental impact

Midpalatal Suture Density Evaluation after Rapid and Slow Maxillary Expansion with a Low-Dose CT Protocol: A Retrospective Study

Examination of craniofacial morphology in Japanese patients with congenitally missing teeth: a cross-sectional study

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