Cleistanthus collinus poisoning

Naik, GSivaram; Harikrishna, J; Kumar, D Prabath; Rao, Mangu Hanumantha; Sarma, K.V.S.; Guntupalli, K. K.

doi:10.4103/0971-5916.192068

Cited by 17 publications

(9 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Ingestion of leaves of plant Cleistanthus collinus (CC), is a common way to commit suicide in rural Southern India. CC poisoning appears to be almost exclusive to the Southern Indian states of Tamil Nadu, Pondicherry and the Rayalaseema area of Andhra Pradesh State 1. No single case is reported is from state of Telangana and this is probably a first case to be reported.…”

Section: Introductionmentioning

confidence: 76%

Cleistanthus collinuspoisoning: a case report of intentional poisoning

Bompelli¹,

C²,

Modani³

et al. 2019

BMJ Case Rep

View full text Add to dashboard Cite

We report a case of 50-year-old male patient from tribal area in South Indian state of Telangana, who ingested the liquid extract from crushed leaves of the plant, cleistanthus collinius with the intention of self-harm. Immediate gastric lavage and activated charcoal administration was done and the patient was subsequently admitted into an acute medical care unit. During first 24 hours of monitoring, the patient was clinically stable. There was mild normal anion gap metabolic acidosis and hypokalaemia on arterial blood gas (ABG) and was corrected accordingly. On second day of admission he developed acute onset shortness of breath. Chest auscultation revealed extensive bilateral coarse crackles. Chest X-ray was suggestive of acute respiratory distress syndrome (ARDS). The patient had to be intubated. Continuous renal replacement therapy (CRRT) was initiated in view of worsening metabolic acidosis and unstable haemodynamics. In spite of appropriate intensive care measures, the patient succumbed to illness. Immediate gastric lavage and activated charcoal administration was done and the patient was subsequently admitted into an acute medical care unit. During first 24 hours of monitoring, the patient was clinically stable. There was mild normal anion gap metabolic acidosis and hypokalaemia on ABG and was corrected accordingly. On second day of admission, he developed acute onset shortness of breath. Chest auscultation revealed extensive bilateral coarse crackles. Chest X-ray was suggestive of ARDS. The patient had to be intubated on day 2. CRRT was initiated in view of worsening metabolic acidosis and unstable haemodynamics. In spite of appropriate intensive care measures, the patient gradually deteriorated, had cardiac arrest and passed away on day 5 of his hospital stay.

show abstract

Section: Introductionmentioning

confidence: 76%

Cleistanthus collinuspoisoning: a case report of intentional poisoning

Bompelli¹,

C²,

Modani³

et al. 2019

BMJ Case Rep

View full text Add to dashboard Cite

show abstract

“…The comparison of group differences for continuous variables was performed using the Kruskal-Wallis test; post hoc analysis was carried out by pairwise comparisons and adjusting the significance level 16 . Worst-case scenario analysis 17 was undertaken where patients who were discharged against medical advice (DAMA) were considered to have the worst outcome i.e ., were considered to be non-survivors.…”

Section: Methodsmentioning

confidence: 99%

Serum procalcitonin as a biomarker of bloodstream infection & focal bacterial infection in febrile patients

Harikrishna

Chakravarthi

Chaudhury

et al. 2020

Indian Journal of Medical Research

Self Cite

View full text Add to dashboard Cite

Background & objectives: Bacteraemia is a serious form of infection in patients presenting with fever, thus, there is a necessity for a biomarker for rapid diagnosis of bacteraemia in such patients to make better therapeutic decisions. This study was conducted to measure the serum procalcitonin (PCT) levels at the time of initial presentation as a biomarker for identifying bacteraemia and as a predictor of mortality in patients admitted with acute fever. Methods: Four hundred and eighty patients, who presented with acute fever requiring admission to a tertiary care teaching hospital in south India, were prospectively studied. All patients were evaluated with a detailed history, physical examination, laboratory and imaging studies. Baseline serum PCT was measured for each patient within six hours of admission. Results: Among patients with single infectious cause (n=275), significantly higher median serum PCT levels were evident in bacteraemia compared to leptospirosis ( P =0.002), dengue ( P <0.001), scrub typhus ( P <0.001) and evident focus of infection without bacteraemia ( P =0.036). By receiver-operator characteristic curve analysis, at a cut-off value of >3.2 ng/ml, the sensitivity and specificity of serum PCT levels in predicting bacteraemia were 81.1 and 63.3 per cent, respectively. As per the worst-case scenario analysis, 91 (18.9%) patients had a poor outcome and these had significantly higher median serum PCT levels compared to survivors (n=389) [9.46 (2.03-44.4) vs. 1.23 (0.34-7.645); P <0.001]. At a cut-off value of >3.74 ng/ml, serum PCT levels at initial presentation predicted in-hospital mortality with a sensitivity and specificity of 67 and 67.5 per cent, respectively. Interpretation & conclusions: Our observations suggest that serum PCT level may be a useful biomarker for identifying bacteraemia as well as predicting mortality in patients with acute fever requiring admission to hospital.

show abstract

“…92,93 Other plants that can cause AKI include certain species of mushroom, 94 and fruits, flowers and roots from plants like Gloriosa superba and Cleistanthus collinus. 95,96 Acute interstitial nephritis and acute tubular necrosis have been described in mushroom poisoning. 97 Similarly, AKI continues to be encountered in the context of chemical poisonings with copper sulfate, paraquat, aluminium phosphide, chromic acid and melamine in milk formulae.…”

Section: Acute Glomerulonephritismentioning

confidence: 99%