The climate change is the main issue in recent decades. Marine and coastal areas are deeply affected by climate change. To investigate the effect of climate change in the southern coast of the Caspian Sea, the variations of main meteorological parameters such as anomaly of minimum and maximum temperature, precipitation, sea surface temperature and, also the frequency of foggy, hazy and dusty days are examined in a 40-year period from 1979 to 2018 (anomalies with respect to the 1981-2010 baseline). The results of the study showed that the significant increasing trend in temperature in all stations that located in industrial and urban area. There is no significant change in precipitation due to complex structure of this parameter in the South Caspian Sea areas. The lake effect and topography play as a key role in generation of precipitation than large scale systems. Also there is highly significant increasing trend of sea surface temperature in South Caspian Sea which is a result of the effects of global warming in that region. There is also an increase in the occurrence of the rare dust phenomenon in that area. The increasing trend of hazy days was observed in all areas, particularly in industrial zones that can affect some meteorological parameters.