Abstract. The Qaidam basin in the north of the Tibetan Plateau, has undergone drastic environmental changes during the last millions of years. During the Pliocene, the basin contained a freshwater mega-lake system although the surrounding regions showed increasingly arid climates. With the onset of the Pleistocene glaciations, lakes began to shrink, and finally disappeared almost completely. Today, hyperarid climate conditions prevail in the low-altitude parts of the basin. The question, how the lake system was able to withstand the regional trend of aridification for millions of years, remained enigmatic, so far. This study reveals that the mean water balance of the basin is nearly zero under present climate conditions, and positive during warmer, less dry years. This finding provides a physically based explanation, how mid-Pliocene climates could sustain the mega-lake system, and that near-future climates not much different from present conditions could cause rising lake levels and expanding lake areas, and may result in restoration of the Qaidam mega-lake system over geological time scales. The study reveals that a region discussed as being an analogue to Mars due to its hyperarid environments is at a tipping point under present climate conditions, and may switch from negative values that have prevailed during the last 2.6 million years to positive ones in the near future.