Dengue, a viral disease, is transmitted by vectors such as Aedes aegypti and Aedes albopictus mosquitoes. A dramatic rise in dengue cases, exacerbated by climate change and urbanization in recent years, has caused public health challenge. Global warming, associated rise in sea level, and unpredictable rainfall accelerate the survival, development, and dispersal of Aedes mosquitoes significantly influencing dengue disease dynamics. Coupled with increased global trade and travel, dengue has spread to previously unaffected areas. Poor urban planning, overcrowding, inadequate sanitation, and improper water storage are important for favorable breeding environment of mosquitoes. Climate change triggers genetic adaptations in both vectors and virus, mostly enhancing their survival and transmissibility and influencing their virulence and epidemic potential. Effective outbreak control requires timely detection and reporting through integrated disease surveillance systems, and sustainable vector control through breeding site elimination and application of insecticides. Despite there is significant progress in vaccine and antiviral development, its implementation needs further research including community involvement and awareness campaigns. Dengue prevention is possible by understanding the interactions of climate, mosquito ecology, and disease transmission and by successful implementation of appropriate interventions. Therefore, integrated approach of public health agencies, policymakers, and communities is crucial to control and mitigate climate-driven dengue transmission.