Climatotherapy in Atopic Eczema

Vocks, E.

doi:10.1007/3-540-29856-8_55

Cited by 11 publications

(18 citation statements)

References 49 publications

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“…Because of the chronic nature of AD, alternative therapies are often considered, such as acupuncture, homeopathy, (15,16). However, the efficacy of these therapies over regular therapy could not be demonstrated (17)(18)(19).Climate therapy has been used since the 20th century for the treatment of various chronic inflammatory dermatoses and pulmonary diseases (20,21). It combines anti-inflammatory treatment in a trigger-free environment with being hospitalized in a specialized clinic for a period of 4 weeks to 3 months.…”

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confidence: 99%

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Alpine climate treatment of atopic dermatitis: a systematic review

Fieten

Weststrate

Zuuren

et al. 2014

Allergy

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Climate therapy has been used for decades in the treatment of atopic dermatitis (AD), but evidence of its effectiveness has not yet been assessed systematically. A systematic literature search in Medline, Embase, and the Cochrane library was performed to identify all original studies concerning alpine climate treatment. The risk of bias of individual studies was assessed following the Cochrane Handbook, and level of evidence was rated using GRADE guidelines. Fifteen observational studies were included concerning 40 148 patients. Four studies concerning 2670 patients presented follow-up data over a period of 1 year. Disease activity decreased in the majority of patients during treatment (96% of n = 39 006) and 12-month follow-up (64% of n = 2670). Topical corticosteroid use could often be reduced or stopped during treatment (82% of n = 1178) and during 12-month follow-up (72% of n = 3008). Quality assessment showed serious study limitations, therefore resulting in a very low level of evidence for the described outcomes. Randomized controlled trials designed with a follow-up period including welldefined patient populations, detailed description and measurement of applied interventions during climate therapy and using validated outcomes including costeffectiveness parameters, are required to improve the evidence for alpine climate therapy as an effective treatment for patients with AD.Atopic dermatitis (AD) is a chronic, inflammatory skin disease characterized by subsequent exacerbations and remissions (1). Its prevalence is increasing worldwide, and AD is currently among the most common skin diseases in children (2). Itching, disturbed sleep, and time-consuming medical treatment regimens lead to a reduced experienced quality of life in patients with AD (3, 4).AD is a complex disease with several genetic and environmental factors involved (5). A genetic predisposition leads to an atopic constitution and a disturbed immune response which results in chronic inflammation and an impaired skin barrier (6, 7). In several eczema birth cohorts, the association between AD and the subsequent development of asthma and allergic sensitization has been established (8, 9). Prevalence of allergic sensitization in children with AD varies between countries, ranging from 52% in Belgium to 83% in Australia (8). Around 30% of children diagnosed with AD will develop asthma later in life (10). Among adults with AD, there is also great variation in prevalence of allergic sensitization and asthma diagnosis (11).Exposure to irritants and allergens, changes in physical environment (pollution, humidity), infections, and psychosocial or emotional factors are possible triggers for exacerbations (12). AD treatment is based on control of inflammation/infection, skin hydration, and trigger avoidance (13,14). Treatment approaches include anti-inflammatory therapy with topical immunosuppressives (dermatocorticosteroids, calcineurin inhibitors) and antimicrobial treatment, according to current guidelines (13,14). In more severe cases, phototh...

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confidence: 99%

“…Climate therapy has been used since the 20th century for the treatment of various chronic inflammatory dermatoses and pulmonary diseases (20,21). It combines anti-inflammatory treatment in a trigger-free environment with being hospitalized in a specialized clinic for a period of 4 weeks to 3 months.…”

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confidence: 99%

Alpine climate treatment of atopic dermatitis: a systematic review

Fieten

Weststrate

Zuuren

et al. 2014

Allergy

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“…6 Furthermore, AD severity is directly related to increased prevalence of asthma, allergic rhinitis or food allergies. 10,11 Alpine climate treatment has been used for decades as a treatment option for asthma and AD in Europe. 8,9 The common elements included in these programmes are education, treatment management and psychological or behavioural interventions aimed at coping with disease.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to improving disease activity, these programmes address itching and scratching, sleep disruption, challenges in disease management including adherence to treatment, psychosocial problems and education of children and their families. 11 Observational studies have shown that alpine climate treatment improves disease activity in the long term. 9 Climate change to seaside or mountain resorts for the treatment of allergic diseases in children has been studied before.…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of alpine climate treatment for children with difficult to treat atopic dermatitis: Results of a pragmatic randomized controlled trial (DAVOS trial)

Fieten

Schappin

Zijlstra

et al. 2017

Clin Experimental Allergy

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“…Immediaterfolge sind eindeutig nachgewiesen [17]. So sind nach einem 4-6-wöchigen Rehabilitationsaufenthalt in Davos in 1600 m Höhe bei Entlassung 92% der Patienten mit Neurodermitis und Asthma bronchiale erscheinungsfrei, 6% leicht gebessert und nur 2% unverändert [18] [42].…”

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Die Evidenz der Klima- und Thalassotherapie. Ein Review

Schuh¹

2009

Schweiz Z Ganzheitsmed

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Hintergrund: Klimatherapie (am Meer: Klima- und Thalassotherapie) wird seit langer Zeit zur Behandlung zahlreicher Krankheitsbilder, insbesondere von Haut- und Atemwegserkrankungen, eingesetzt. Ziel und Fragestellung: FÜr welche Krankheitsbilder ist die Evidenz gesichert? Methode: Systematische Auswertung der wissenschaftlichen Literatur der gÄngigen Datenbanken von 1988 bis 2008. Ergebnisse: Die einzelnen Wirkfaktoren der Klimatherapie sind evident. FÜr die Klimatherapie von atopischen Erkrankungen (Neurodermitis, Asthma bronchiale) und Trainingsmangel im Hochgebirge sind eindeutige Daten Über akute und langfristige Erfolge vorhanden. Bei der Psoriasis ist grÖsste Evidenz fÜr die Therapie im Hochgebirgsklima sowie fÜr die Klima- und Thalassotherapie am Toten Meer gegeben. Auch bei weiteren Indikationen der Klimatherapie, wie den «funktionellen» StÖrungen des Herz-Kreislaufsystems, sprechen die Studienergebnisse fÜr eine anhaltende Reduzierung der Symptome, vor allem im Bereich des Hochgebirgsklimas. FÜr die AbhÄrtung an der See liegen genÜgend Daten vor. Trotzdem sind die therapeutischen Effekte der Klima- und Thalassotherapie noch verhÄltnismÄssig unsicher, vor allem fÜr die am meisten bekannten Indikationen Psoriasis, Neurodermitis und Asthma bronchiale. Schlussfolgerung: FÜr die meisten bekannten Indikationen der Klimatherapie und zum Teil der Thalassotherapie ist Evidenz fÜr akute und langfristige Effekte vorhanden. Voraussetzung ist die Wahl der richtigen Klimazone.

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Climatotherapy in Atopic Eczema

Cited by 11 publications

References 49 publications

Alpine climate treatment of atopic dermatitis: a systematic review

Alpine climate treatment of atopic dermatitis: a systematic review

Effectiveness of alpine climate treatment for children with difficult to treat atopic dermatitis: Results of a pragmatic randomized controlled trial (DAVOS trial)

Die Evidenz der Klima- und Thalassotherapie. Ein Review

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