Clindamycin Vaginal Insert

Halliday, J. Peter; Robertson, Steve

doi:10.3109/9781420045260-40

Cited by 2 publications

(1 citation statement)

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“…[135][136][137][138][139] In 2012, Francisco Trotta et al developed cyclodextrin-based nanosponges, which have been heralded as a revolutionary nanosized delivery system (Table 10). [140][141][142][143][144][145][146][147][148][149][150][151][152][153][154][155][156][157][158][159]…”

Section: Active Drug Methods Of Preparationmentioning

confidence: 99%

A Novel Approach on Micro Sponges Drug Delivery System: Method of Preparations, Application, and its Future Prospective

Mandal,

Km Bhumika,

Kumar

et al. 2023

Ind. J. Pharm. Edu. Res

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Microsponges are porous microspheres ranging in size from 5 to 300 micrometers used in a polymeric delivery system. They have been studied for biomedical applications, including targeted medicine delivery, transdermal drug delivery, anticancer drug delivery, and bone substitutes. This research aims to conduct a detailed examination of existing trends and future prospects for a microsponge-based medicine delivery system. The current study investigates the Microsponge Delivery System's design, operation, and possible therapeutic uses (MDS). The therapeutic potential of microsponge-based formulations, as well as patent data, were thoroughly investigated. The authors discuss several efficient methods for producing microsponges, including liquid-liquid suspension polymerization, quasi-emulsion solvent diffusion, water-in-oil-in-water (w/o/w) emulsion solvent diffusion, oil-in-oil emulsion solvent diffusion, the lyophilization method, the porogen addition method, the vibrating orifice aerosol generator method, the electrohydrodynamic atomization method, and the ultrasound-assisted microsponge. Microsponge may reduce undesired side effects and increase drug stability by boosting drug release. Hydrophilic and hydrophobic drugs can be loaded into a microsponge and transported to a specific target. When compared to traditional distribution methods, microsponge delivery technology offers numerous advantages. Microsponges, which are spherical, sponge-like nanoparticles with porous surfaces, can help increase drug stability. They efficiently alter drug release while also reducing adverse effects.

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