Clinical Advances in Triple Negative Breast Cancer Treatment: Focus on Poly (L-lactide-coglycolide) Nanoparticles

Special Section on Nanotherapeutics in Cancer Research—Editorial

“…Conversely, an in vitro research study by Mao and his group outlines the neurotoxic disadvantages of aluminum salt-based NPs as adjuvants for therapeutic cancer vaccines (Chen et al, 2024). A following review by Towner, Dissanayake, and Ahmed outlines clinical advances of lead compound PLGAbased NPs for metastatic triple-negative breast cancer (TNBC) as well as current clinical therapies that may be beneficial when combined with NP composites (Towner et al, 2024). In keeping with the breast cancer theme, an in vitro and preclinical in vivo research study in mice by Harrison and his group presents a photothermal therapy using anti-PD-1-targeted carbon nanotubes as a potential treatment strategy for metastatic breast cancer (Faria et al, 2024); which is followed by an in vitro research investigation by Ahmed and her group that focuses on the use of biocompatible polydopamine core-shell NPs as a potential therapy for breast cancer (Steeves et al, 2024).…”