Background and aim
Diabetic maculopathy is a leading cause of visual loss in diabetic patients. The choroid is the outer retina's primary source of oxygen and nourishment and the only blood supply to the avascular fovea. Angiopathy of the choroid seems to have a role in the pathophysiology and progression of diabetic maculopathy. It has been theorized that unexplained visual acuity loss in diabetic patients might be linked to diabetic choroidopathy. The aim of this study was to evaluate choroidal changes in eyes with diabetic maculopathy using optical coherence tomography.
Patients and methods
In all, 20 eyes of 10 normal individuals and 94 eyes of 50 diabetic patients suffering from diabetic maculopathy were recruited in this study. The diabetic patients were categorized according to the type of maculopathy as demonstrated by fluorescein angiography into four subgroups: the focal edema group, the diffuse edema group, the ischemic maculopathy group, and the mixed maculopathy group. Choroidal thickness was measured subfoveally, 1 mm away from the fovea nasally, temporally, superiorly, and inferiorly using optical coherence tomography.
Results
There was a significant difference among the different groups in all the measured regions (P=0.001). The more severe the maculopathy, the thinner the choroid in all the measured regions.
Conclusion
The results of this study suggest a negative relationship between macular choroidal thickness and severity of diabetic maculopathy.