Clinical Analysis of Postoperative Complications in 1, 000 Cases of Intracranial Saccular Aneurysms

Takaku, Akira; Tanaka, Satoru; Mori, Takeshi; Shindou, Kenjiro; Fukawa, Osamu; Hen, R C; Suzuki, Jirô

doi:10.2176/nmc.18pt2.191

Cited by 6 publications

(9 citation statements)

References 7 publications

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“…11,19,27,29,57,61,70 In these studies, 17 of 686 patients died after operation (2.5%; 95% CI, 1.5% to 3.9%). Data on morbidity were available in 5 of 7 studies: 80 of 629 patients had postoperative sequelae (12.7%; 95% CI, 10.1% to 15.3%).…”

Section: Subgroup Analysis Of Studies Of Good Qualitymentioning

confidence: 94%

Mortality and Morbidity of Surgery for Unruptured Intracranial Aneurysms

Raaymakers

Rinkel

Limburg

et al. 1998

Stroke

457

240

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Background and Purpose-Greater availability and improvement of neuroradiological techniques have resulted in more frequent detection of unruptured aneurysms. Because prognosis of subarachnoid hemorrhage is still poor, preventive surgery is increasingly considered as a therapeutic option. Elective surgery requires reliable data on its risks. Therefore, we performed a meta-analysis on the mortality and morbidity of surgery for unruptured intracranial aneurysms. Methods-Through Medline and additional searches by hand, we retrieved studies on clipping of unruptured (additional, symptomatic, or incidental) aneurysms published from 1966 through June 1996. Two authors independently extracted data. We used weighted linear regression for data analysis. Results-We included 61 studies that involved 2460 patients (57% female; mean age, 50 years) and at least 2568 unruptured aneurysms (27% Ͼ25 mm, 30% located in the posterior circulation). Mortality was 2.6% (95% confidence interval [CI], 2.0% to 3.3%). Permanent morbidity occurred in 10.9% (95% CI, 9.6% to 12.2%) of patients.Postoperative mortality was significantly lower in more recent years for nongiant aneurysms and aneurysms with an anterior location; the last 2 characteristics were also associated with a significantly lower morbidity. Conclusions-In studies published between 1966 and 1996 on clipping of unruptured aneurysms, mortality was 2.6% and morbidity was 10.9%. In calculating the pros and cons of preventive surgery, these proportions should be taken into account. (Stroke. 1998;29:1531-1538.)

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Section: Subgroup Analysis Of Studies Of Good Qualitymentioning

confidence: 94%

Mortality and Morbidity of Surgery for Unruptured Intracranial Aneurysms

Raaymakers

Rinkel

Limburg

et al. 1998

Stroke

457

240

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“…The mean (SD) speed quotient was 99-25 (10-8) compared with an expected score of 100 (15), the mean scale score for the WAIS. Similarities were 9-5 (2 5) compared with an expected score of 10 0 (3 0).…”

Section: B) One Year Assessmentmentioning

confidence: 96%

The cognitive and psychological sequelae of uncomplicated aneurysm surgery.

Maurice‐Williams¹,

Willison²,

Hatfield³

1991

Journal of Neurology, Neurosurgery & Psychiatry

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“…Of the 19 patients, 17 had an excellent or good outcome. Excellent or good results were reported between 50.4% and 90.6% of cases in the literature (14,23,29). Lee et al reported poor results in 126 patients with DACA aneurysms and the mortality rate was 0.9% (14).…”

Section: █ Discussionmentioning

confidence: 97%

“…The ages of the patients vary from 40.6 to 54 years in most of the publications (3)(4)(5)8,10,13,29,31). In our study, the ages of the patients were between 19 and 76 years with a mean age of 34 years and this result is similar with the literature (3)(4)(5)8,10,13,29,31). In our patient population, the female/male ratio was 4:1 and a female predominance is seen in the majority of the publications in varying proportions as 1.2:1 to 2:1 (2,12).…”

Section: █ Discussionmentioning

confidence: 99%