Clinical, Anatomical, and Physiologic Relationship Between Sleep and Headache

Dodick, David W.; Eross, Eric J.; Parish, James M.

doi:10.1046/j.1526-4610.2003.03055.x

Cited by 232 publications

(183 citation statements)

References 28 publications

Supporting

Mentioning

168

Contrasting

Unclassified

Order By: Relevance

“…reported -to a hypothalamic involvement [3]. Clinical observations show, indeed, that migraine attacks have a seasonal, menstrual and circadian timing, suggesting a role of chronobiological mechanisms and their alterations in the disease, but little experimental data exists on this issue.…”

Section: Sara Gori Nicola Morelli Michelangelo Maestri Monica Fabbrinmentioning

confidence: 99%

Sleep quality, chronotypes and preferential timing of attacks in migraine without aura

et al. 2005

View full text Add to dashboard Cite

IntroductionThe relationship between sleep and headache has been known for over a century. Headache and sleeping problems are both some of the most commonly reported problems in clinical practice, and cause considerable social and family problems, as well as socio-economic impact and costs. Much data suggests an association between headache, especially migraine, on one side and sleep and its disorders on the other, but the cause and effect of this relationship is not clear. With regard to migraine, rest and sleep usually bring relief and have therefore been attempted in the treatment strategy; on the other hand however, migraine episodes are frequently triggered by several factors including sleep pattern changes; emotional stress, hypoglycaemia, sensorial stimulation (loud noise, bright light, heat or cold) and also lack of sleep or excess (weekend migraine) may, indeed, represent migraine triggers. Premonitory symptoms like mood states such as alert, tense, depressed or tired and changes in sleep quality have been described to occur up to 2 days before a migraine attack and were hypothesised to be related to a hypothalamic involvement in the prodromic phase of migraine [1]. Recently it has also been documented that overuse of migraine symptomatic drugs may worse sleep pattern in migraineurs and the withdrawal of the misused medication can alleviate the associated sleep disturbance [2].Several findings also suggest a role of chronobiological factors in migraine, probably related -as previously J Headache Pain (2005) 6:258-260 DOI 10.1007/s10194-005-0201-2 Sleep quality, chronotypes and preferential timing of attacks in migraine without aura Abstract Clinical observations show that migraine attacks have a seasonal, menstrual and circadian timing, suggesting a role of chronobiological mechanisms and their alterations in the disease, but little experimental data exists about this issue. The aim of this study was to estimate sleep quality chronotypes, and the possible circadian timing of attacks in migraneurs. One hundred patients suffering from migraine without aura according to the IHS criteria (2004), and 30 controls were enrolled. Morning and evening type subjects were more represented in migraine patients than in controls and showed a tendency towards worse sleep quality and higher disability. Forty-two percent of migraineurs presented more than 75% of their attacks at night. Morning and evening types rather than intermediate and differences between real and preferred times may represent stressors that can worsen the disease. A preferential timing for occurrence of migraine attacks during the night and early morning hours was documented. P S Y C H O B I O L O G I C A L A S P E C T S O F H E

show abstract

Section: Sara Gori Nicola Morelli Michelangelo Maestri Monica Fabbrinmentioning

confidence: 99%

Sleep quality, chronotypes and preferential timing of attacks in migraine without aura

et al. 2005

View full text Add to dashboard Cite

show abstract

“…Migräne: Es gibt eine Vielzahl von unterschiedlichen Beobachtungen, die eine Wechselbeziehung zwischen Migräne und Schlaf belegen: Schlafentzug und Änderungen eines festen Tag-NachtRhythmus sind ein möglicher Auslöser für Attacken (sog. Weekend-Migräne; [6,11]). Umgekehrt können Migräneatta-cken auch direkt aus dem Schlaf heraus auftreten, wobei dabei wahrscheinlich der REM-Schlaf-Phase besondere Bedeutung zukommt (Übersicht in: [11] Möglicherweise gibt es jedoch Unterschiede zwischen der chronischen und der episodischen Form [26,42].…”

Section: Literaturübersichtunclassified

Schlafverhalten und Kopfschmerzattacken bei prim�ren Kopfschmerzen

Straube

Förderreuther

2004

Schmerz

View full text Add to dashboard Cite

Headache is connected with sleep quality, e.g. hypnic headache and chronic paroxysmal headache attacks occur preferentially during REM sleep; this is possibly also true for cluster headache and migraine. REM sleep is typically characterized by the occurrence of ponto-geniculo-occipital spikes (PGOs). These PGOs should be able to trigger cortical spreading depression (CSD), which, although often clinically silent, is assumed to be an essential element of a migraine attack and possibly also of other forms of headache. CSDs are considered a correlate of migraine aura. They could lead to the secondary activation of trigeminovascular afferences, which would then induce a headache. Interestingly, illnesses that are comorbid with migraine cause an increase in the amount of REM sleep; conversely, various drugs administered prophylactically for these illnesses reduce the quantity of REM sleep.

show abstract

“…A recent survey involving the United Kingdom, Germany, Portugal, Spain and Italy showed that nearly 8% of the sample reported to wake up with headaches [14]. Most headaches related to sleep disorders often lack distinguishing features, are poorly localised and occur after extensive sleep disruption [3].…”

Section: Introductionmentioning

confidence: 99%

Morning headaches, daytime functioning and sleep problems – a population-based controlled study

Seidel

Klösch

Moser

et al. 2010

Wien Klin Wochenschr

View full text Add to dashboard Cite

The aim of this paper was to assess the prevalence of morning headaches in the Austrian general population and to analyse their relationship to daytime functioning and quality of sleep. In a nationwide survey, we recruited 1000 adults (478 men, 522 women, age over 14 years). For this study, we selected all subjects with self-reported morning headaches as well as controls matched for age, sex, size of hometown, level of education and marital status. Forty-eight persons reported morning headaches making a prevalence of 5% in the Austrian general population. Compared to controls, subjects with morning headaches reported more often daytime sleepiness (50% vs. 18.8%, p = 0.003), difficulties in staying awake (47.9% vs. 18.8%, p = 0.005) and falling asleep involuntarily (29.2% vs. 8.3%, p = 0.019). Moreover, they reported a longer sleep onset latency (26.5 ± 27.5 vs. 13.5 ± 13.5 min, p = 0.005), and more often sleep disturbances (58.3% vs. 14.6%, p < 0.001), tossing and turning around during the night (50.0% vs. 8.0%, p < 0.001), problems with sleep maintenance (64.6% vs. 22.9%, p < 0.001) and the symptom of restless legs (20.8% vs. 2.1%, p = 0.01). In addition, subjects with morning headaches felt less often refreshed in the morning (18% vs. 51%, p < 0.001) and reported regular use of medication more often (64.6% vs. 29.2%, p = 0.001) than controls. After correction for multiple testing, the differences in sleep maintenance, sleep disturbances and regular use of medication remained statistically significant. In conclusion, this is the first Austrian population-based controlled study to show that morning headaches afflict one out of 20 persons and are related to self-reported sleep problems.

show abstract

Clinical, Anatomical, and Physiologic Relationship Between Sleep and Headache

Cited by 232 publications

References 28 publications

Sleep quality, chronotypes and preferential timing of attacks in migraine without aura

Sleep quality, chronotypes and preferential timing of attacks in migraine without aura

Schlafverhalten und Kopfschmerzattacken bei prim�ren Kopfschmerzen

Morning headaches, daytime functioning and sleep problems – a population-based controlled study

Contact Info

Product

Resources

About