Clinical and antimicrobial evaluation of a mouthwash and toothpaste for xerostomia: A randomized, double-blind, crossover study

López-Jornet, M.P.; García-Teresa, G.; Viñas, Miguel; Vinuesa, Teresa

doi:10.1016/j.jdent.2011.08.007

Cited by 18 publications

(17 citation statements)

References 28 publications

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“…In the study of Gil Montoya et al ( 25 ) it was tested against a placebo, evaluating dry mouth symptoms and showing no differences between the two groups. In the study by López-Jornet et al ( 26 ) it is compared with a mouthwash with triclosan (antiseptic) and remineralising ingredients, such as fluorides and mineral salts. An improvement of symptoms was found with the triclosan mouthwash and also a significant decrease of cariogenic bacteria.…”

Section: Resultsmentioning

confidence: 99%

Treatment of xerostomia and hyposalivation in the elderly: A systematic review

Gil-Montoya

Silvestre²,

Barrios³

et al. 2016

Med Oral

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BackgroundTherapeutic strategies for xerostomia, regardless of etiology, have so far not had definitive or clearly effective results. Objectives. To systematically revise the latest scientific evidence available regarding the treatment of dry mouth, regardless of the cause of the problem.Material and MethodsThe literature search was conducted in March 2015, using the Medline and Embase databases. The “Clinical Trial”, from 2006 to March 2015, was carried out in English and only on human cases. The draft of the systematic review and assessment of the methodological quality of the trials was carried out following the criteria of PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and the “Oxford Quality Scale”.ResultsFinally, a total of 26 trials were identified that met the previously defined selection and quality criteria; 14 related to drug treatments for dry mouth, 10 with non-pharmacological treatment and 2 with alternative treatments.ConclusionsPilocarpine continues to be the best performing sialogogue drug for subjects with xerostomia due to radiation on head and neck cancer or diseases such as Sjogren’s Syndrome. For patients with dry mouth caused solely by medication, there are some positive indications from the use of malic acid, along with other elements that counteract the harmful effect on dental enamel. In general, lubrication of oral mucous membrane reduces the symptoms, although the effects are short-lived. Key words:Systematic review, xerostomia, clinical trial, hyposalivation.

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Section: Resultsmentioning

confidence: 99%

Treatment of xerostomia and hyposalivation in the elderly: A systematic review

Gil-Montoya

Silvestre²,

Barrios³

et al. 2016

Med Oral

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“…diet modification, fluoride delivery and improved oral hygiene . In patients with impaired salivary gland function, due to aging, radiotherapy, diseases or medications, the administration of salivary substitutes to buffer the acidic environment and inhibit adhesion and growth of bacteria might also be of help .…”

Section: Root Caries: Preventive and Therapeutic Considerationsmentioning

confidence: 99%

Root caries: a periodontal perspective

Bignozzi

Crea²,

Capri³

et al. 2013

J of Periodontal Research

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Research regarding root caries in age-specific (elderly) periodontal patients is needed. Improved oral hygiene practices, locally applied preventive measures, good dietary habits and regular dental check-ups are crucial approaches to prevent both periodontal disease progression and root caries. Periodontal patients with root exposure should follow a strict root caries prevention protocol, as an integral component of their periodontal maintenance therapy.

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“…En los pacientes con xerostomía, es de suma importancia que el tratamiento incluya evaluaciones dentales frecuentes, las instrucciones de higiene oral son esenciales para prevenir la caries y otras infecciones orales (34), en el caso reportado el uso de nistatina en enjuagues una vez al día como mantenimiento favoreció que no tuviera más infecciones fúngicas. El uso de pasta dental y enjuague bucal a base de triclosán, fluoruro, revitalizadores gingivales y sales minerales, mejora la calidad de vida de los pacientes que sufren xerostomía; se deben evitar los que incluyan laurilsulfato de sodio, aromas fuertes y alcohol ya que agravarían la sequedad oral exacerbando los síntomas (35). El Kin Hidrat® pasta, colutorio y spray es una buena opción ya que contienen ácido cítrico, flúor y xilitol; en nuestro caso le ayudó inicialmente a la paciente.…”

Section: Reporte De Casounclassified

Sjögren Syndrome and Mucous Membrane Pemphigoid in a Patient with a History of Thymoma: Case Report and Literature Review

Oreamuno

Tinoco

Guillén

2019

Odovtos - Int J Dent Sc

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Thymomas are the most common mediastinal neoplasms in adults. Patients with thymoma are frequently diagnosed with paraneoplastic syndromes and are generally associated with several autoimmune conditions. Sjögren's syndrome (SS) is an autoimmune inflammatory disorder, characterized by the lymphocyte-mediated destruction of the exocrine glands, which leads to the absence of glandular secretion, particularly salivary and lacrimal; hyposalivation can vary from a slight reduction in the flow of saliva with transient discomfort, to a serious deterioration of oral health and psychological distress. Mucous membrane pemphigoid (MMP) is a chronic, autoimmune disease that shows predominant mucosal involvement, most commonly affecting the oral cavity, followed by the conjunctiva, the nasal cavity and the esophagus; intraorally includes scaly gingivitis, vesicles, erosions covered by pseudomembranes and ulcers. The objective of this work is to present the first case of a patient with a history of thymoma, which, jointly presented SS and MMP; also highlight the importance of multidisciplinary management for an accurate and early diagnosis, as this increases the efficiency and efficacy of the treatment strategy.

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Clinical and antimicrobial evaluation of a mouthwash and toothpaste for xerostomia: A randomized, double-blind, crossover study

Cited by 18 publications

References 28 publications

Treatment of xerostomia and hyposalivation in the elderly: A systematic review

Treatment of xerostomia and hyposalivation in the elderly: A systematic review

Root caries: a periodontal perspective

Sjögren Syndrome and Mucous Membrane Pemphigoid in a Patient with a History of Thymoma: Case Report and Literature Review

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