Clinical and biochemical effects of propofol EDTA vs sevoflurane in healthy infants and young children¹

Abstract

In children younger than 3 years of age, propofol containing ethylenediaminetetraacetic acid has a similar profile to sevoflurane with respect to haemodynamic effects, recovery times, side-effects, ionized calcium and ionized magnesium levels.

Comparative evaluation of cost effectiveness and recovery profile between propofol and sevoflurane in laparoscopic cholecystectomy

“…observed similar results with no difference in vomiting episodes in their study groups. [ 14 ] Caverni et al . compared sevoflurane and propofol in patients undergoing long-term craniofacial surgeries, and found no differences in postoperative complication in between the groups.…”

Hemodynamic differences between propofol–remifentanil and sevoflurane anesthesia for repair of cleft lip and palate in infants

“…Total intravenous anesthesia (TIVA) with remifentanil and propofol is widely used in adults and pediatric patients, but few randomized studies have been carried out in infants (1,2). Remifentanil has the advantage of not being accumulated as it has a context‐sensitive half‐time that remains constant, and in infants the clearance furthermore is greater than in older age groups (3).…”

Effects of sevoflurane anesthesia on righting reflex and hemolymph gas analysis variables for Chilean rose tarantulas (Grammostola rosea)

“…In human children and adults, sevoflurane anesthesia does not cause changes in serum ionized magnesium concentration. 40,41 Significant increases in serum ionized magnesium concentration were detected in another study 42 for cats and dogs undergoing sevoflurane anesthesia for performance of surgical procedures; however, this result was confounded by the fact that fluids with a low concentration of magnesium were administered during the procedures. 42 More likely, the increase in hemolymph sample ionized magnesium concentration detected in the present study was attributable to activity of the spiders.…”