Clinical and cosmetic results of breast boost radiotherapy in early breast cancer: A randomized study between electron and photon

The Incidence of breast cancer has been steadily increasing in the last two decades, more so in urban areas of the sub-continent. Cancer ceters across the country have large numbers of patients being treated with multiple publications in this field. Inspite of paucity of prospective data and randomised clinical trials from India, there are large number of retrospective publications on various aspects of the disease including pathology, radiology, surgery, chemotherapy, radiation, palliative care and alternatitive treatment modalities. These published data provide an insight into the trends of breast cancer in the country and this comprehensive data review of Indian data will provide a basis for designing trials relevant to our population and planning health care.

show abstract

“…However, in centers where electron beam therapy is not available, 3DCRT photon can be used effectively for tumor bed boost. [ 46 ]…”

Section: Indian Data On Radiotherapymentioning

confidence: 99%

Breast cancer: An overview of published Indian data

Rangarajan

Shet

Wadasadawala

et al. 2016

South Asian J Cancer

View full text Add to dashboard Cite

show abstract

“…Dicha toxicidad se mantiene aceptable al plantear luego de la sobreimpresión un tratamiento hipofraccionado [34][35][36][37].…”

Section: Resultsunclassified

“…La sobre impresión (16 Gy en 8 fracciones) con fotones en comparación con electrones no demuestra una diferencia estadísticamente significativa en cuanto a toxicidad aguda, tardía o efectos cosméticos (a dos años) [34]. Al comparar la sobreimpresión de forma secuencial o integrada, se evidencia que no hay una diferencia en cuanto al efecto descamación húmeda, encontrando si una diferencia significativa a favor del tratamiento integrado en cuanto a dermatitis grado 2 y prurito [36].…”

Section: Resultsunclassified

Tratamiento radiante adyuvante del lecho quirúrgico en el cáncer de mama: a quién, cuándo y cómo hacerlo

Roldán¹,

Guzmán²,

Torres³

et al. 2022

Rev. Oncol. Ecu.

View full text Add to dashboard Cite

Introducción: Actualmente existen discrepancias en cuanto a la indicación, dosis, técnica y contorneo de la sobreimpresión o aumento de dosis de irradiación sobre el lecho quirúrgico en el tratamiento adyuvante en cáncer de mama. Propósito de la revisión: El objetivo de la revisión es presentar la evidencia disponible en sobreimpresión del lecho quirúrgico en el tratamiento de cáncer de mama. Realizamos una revisión bibliográfica en MEDLINE pubmed, se analizaron 61 estudios publicados entre enero del 2000 a enero del 2022. Recientes hallazgos: La sobreimpresión sobre el lecho quirúrgico en la mama mejora el control local en aquellas pacientes con elementos de alto riesgo. Las diferentes técnicas disponibles son oncológicamente equivalentes. La delimitación del blanco de tratamiento debe guiarse por los clips quirúrgicos. Conclusiones: La indicación de dicho tratamiento deberá ser evaluado por los servicios de oncología radioterápica, definiendo sus protocolos y algoritmos de acción.

show abstract

“…Boost radiotherapy treatments were delivered with 3D-CRT photons. 10,11 The boost was delivered with a dose of 9–12 Gy in 3–4 fractions. 12…”

Section: Methodsmentioning

confidence: 99%

Comparison of different registration methods in cone-beam computed tomography for breast boost radiation therapy

Lastrucci

Fedeli²,

Marciello³

et al. 2022

J Radiother Pract

View full text Add to dashboard Cite

Introduction: The aim of this study is to compare patient geometrical uncertainties in the treatment of breast boost three-dimensional conformal radiation therapy (3D-CRT) considering both manual alignment and automatic different registration methods in cone-beam computed tomography (CBCT). Methods: A total of 85 patients were chosen for this study. A total of 254 registrations of CBCT vs planning computed tomography (CT) were retrospectively performed using automatic registration algorithms from Elekta XVI system (Clipbox and Mask) to detect patient setup uncertainties. All CBCTs were also matched manually by three health professionals. Mean shift values obtained with manual registration performed by health professionals were used as reference. Absolute value of difference between automatic algorithm shifts and reference values shifts was collected for each enrolled patient considering the three different spatial directions (x, y ,z), and the magnitude was calculated (δm for Mask and δc for Clipbox). Results: Data analysis showed a significant difference in δm and δc. t-Test statistics showed a high difference between Mask and Clipbox, in particular mean δm = (1.3 ± 0.1) mm and δc = (3.3 ± 1.2) mm (p-value <0.0001). Mask algorithm was performed in a very similar way with respect to the reference alignment, and the differences between these two procedures were of the order of 1 mm. Clipbox algorithm showed larger differences with manual registration. Conclusions: These results suggest that the Mask algorithm may be the optimal choice for patient setup verification in clinical practice for breast boost treatment in 3D-CRT.

show abstract

Clinical and cosmetic results of breast boost radiotherapy in early breast cancer: A randomized study between electron and photon

Cited by 11 publications

References 23 publications

Breast cancer: An overview of published Indian data

Breast cancer: An overview of published Indian data

Tratamiento radiante adyuvante del lecho quirúrgico en el cáncer de mama: a quién, cuándo y cómo hacerlo

Comparison of different registration methods in cone-beam computed tomography for breast boost radiation therapy

Contact Info

Product

Resources

About