Clinical and demographic features of minor salivary gland tumors: A collaborative study of 480 cases

Abstract

Salivary gland tumors are important lesions in head and neck pathology. Although uncommon, they are not rare. As reported in studies, the annual incidence in the world is around 1 to 6.5 cases per 100,000. Most of these tumors occur in major salivary glands and are of epithelial origin. In minor salivary glands, these neoplasms range from 9% to 23% (de Lima et al., 2015). The great diversity of histological types, including the new entities recently described, makes it difficult to appreciate clinical and demographic aspects of salivary gland neoplasms.Brazil is a country with continental dimensions that have geographic and cultural variations. Studies show a frequency of salivary gland tumors in the Brazilian population between 0.25% and 2.6% (da Silva et al., 2018;Loiola et al., 2009), with malignant lesions being responsible for 28.9% to 57.7% of lesions in minor salivary glands, according to the region analyzed (Cunha et al., 2020;da Silva et al., 2018).

Clinical behavior of recurrent pleomorphic adenoma in the palate: a systematic review

“…The demographic factors of RPA found in this review was in accordance with other studies 7,8,34,35 : the tumor occurred mainly in women (61.1%), and the average age of patients was 49.3 years old, contrasting only with one study that found higher frequency of RPA in men than women 36 . The patients with RPA were younger at time of diagnosis of the primary pleomorphic adenoma (mean 33 years old -four patients were < 20 years old and six patients were in their twenties), reinforcing the incidence of palatal benign minor salivary gland at earlier age [1][2][3]6,8,36 .…”

“…Pleomorphic adenoma is the most common type of benign salivary gland tumor and may develop in the major and in the minor salivary glands 1 , 2 . Approximately more than 30% of the pleomorphic adenomas arise in the minor salivary glands, and half of these cases occur in the palate 2 , 3 .…”

“…Pleomorphic adenoma is the most common type of benign salivary gland tumor and may develop in the major and in the minor salivary glands 1 , 2 . Approximately more than 30% of the pleomorphic adenomas arise in the minor salivary glands, and half of these cases occur in the palate 2 , 3 . Clinically, pleomorphic adenoma in palate has good prognosis, and it typically appears as a slow growing and asymptomatic solitary nodule, completely or partially surrounded by capsule, that may cause compressive bone resorption 1 .…”