Clinical and Electrophysiological Characteristics of Binodal Disease

Aortic pulse wave velocity predicts mortality in chronic kidney disease stages 2–4

“…Recently, it has been reported that the SCN5A mutation is associated with progressive AVB [22][23][24]. Association between sick sinus syndrome and various-degree AVB, so-called binodal disease, has been reported [25][26][27]. However, we could not find that association between sick sinus syndrome and first-degree AVB.…”

Minimizing right ventricular pacing in patients with sinus node disease and prolonged PQ interval: The impact on exercise capacity

“…Two thirds of these patients have first degree AV block [8,9]. Prolonged AV conduction may lead to diastolic mitral regurgitation and in some patients may decrease exercise capacity [10,11].…”