Clinical and endoscopic predictors of colorectal adenoma recurrence after colon polypectomy

Jang, Eun Sun; Kim, Ji Won; Jung, Yong Jin; Jeong, Joseph H.; Kim, Byeong Gwan; Lee, Kook Lae; Kim, Sang Woo; Jung, Hyun Chae; Song, In Sung

doi:10.4318/tjg.2013.0610

Cited by 10 publications

(8 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients without a baseline adenoma have a quantifiable risk of AA within 1−5 years. In accordance with other studies, we found that patients with an increased number (≥3 NAA) and with both proximal and distal NAAs at baseline had an increased risk of subsequent adenomas. As in other studies we found that age ≥50 years, male gender and a family history of CRC were also associated with colon neoplasia during follow‐up and that over 50 years old and male gender were independent factors for AA .…”

Section: Discussionsupporting

confidence: 92%

Low rate of advanced adenoma formation during a 5‐year colonoscopy surveillance period after adequate polypectomy of non‐advanced adenoma

Wang

Cao

et al. 2016

Colorectal Disease

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Low rate of advanced adenoma formation during a 5‐year colonoscopy surveillance period after adequate polypectomy of non‐advanced adenoma

Wang

Cao

et al. 2016

Colorectal Disease

View full text Add to dashboard Cite

show abstract

“…Variable rates of RRA continue to challenge the effectiveness of colorectal EMR. Several studies have been conducted to find potential clinical and endoscopic predictors for recurrence 2 3 7 8 9 10 19 20 . A recent metanalysis of 30 articles and 3404 patients undergoing EMR reported an overall rate of recurrence of 13.1 % 17 .…”

Section: Discussionmentioning

confidence: 99%

“…Intralesional and extralesional risk factors for adenoma recurrence after EMR have been well described in multiple studies 2 7 8 9 10 11 . A more recent prospective multicenter study by Tate et al 12 proposed a scoring model for stratification of recurrence risk after EMR.…”

Section: Introductionmentioning

confidence: 96%

Adenoma recurrence after endoscopic mucosal resection: propensity score analysis of old and new colonoscopes and Sydney recurrence tool implementation

et al. 2018

View full text Add to dashboard Cite

Background and study aims Risk factors for colorectal adenoma recurrence after endoscopic mucosal resection (EMR) have been well documented. We assessed the efficacy of the newer 190 colonoscope versus the standard 180 colonoscope for complete resection of lateral spreading lesions. Patients and methods A single-center, retrospective study of patients who underwent EMR with Olympus 180 or 190 colonoscopes from January 1, 2010 to September 30, 2016. We included patients with lesions ≥ 20 mm and surveillance colonoscopy (SC1) after index EMR. A propensity score approach with inverse probability weighting was used to control for potential confounders. A secondary aim was to identify risk factors for recurrence and assess the applicability of the Sydney EMR recurrence tool (SERT) by grading each lesion of our cohort and analyzing associations with recurrence. Results Two hundred ninety-one lesions met inclusion criteria for the study. Odds ratio (OR) for recurrence with the 190 colonoscope was 1.06 ( P = .85). Adenoma size ( P = .02) and use of argon plasma coagulation (APC; P < .001) were risk factors for recurrence. Lesions with SERT scores > 0 had a higher recurrence risk during follow-up (32 % vs 21 %; OR 1.71; P = .05). Lesions with SERT scores = 0 reached a plateau for recurrence at 12 and 18 months in Kaplan-Meier curves. Conclusions The use of 190 colonoscopes did not measurably affect adenoma recurrence at SC1. Recurrence was associated with adenoma size, complementary APC for resection, and SERT scores > 0. Lesions with SERT scores = 0 that remain negative for recurrence at 18 months may return to routine surveillance.

show abstract

“…Several studies reported that older age and male sex were associated with a higher risk of adenoma recurrence. [ 9 12 23 24 ] However, data regarding the influence of modifiable risk factors, such as metabolic factors, on adenoma recurrence are extremely limited. Thus, we conducted this longitudinal study to identify patient-related risk factors associated with the occurrence of colorectal adenomas at time of follow-up surveillance colonoscopy, especially focusing on metabolic factors.…”

Section: Introductionmentioning

confidence: 99%

Metabolic syndrome is a risk factor for adenoma occurrence at surveillance colonoscopy

Kim

Park²,

Park³

et al. 2016

Medicine

View full text Add to dashboard Cite

We investigated the risk factors for adenoma occurrence at surveillance colonoscopy, especially focusing on patient characteristics, including metabolic factors.Surveillance colonoscopy intervals depend on baseline adenoma characteristics. However, patients’ characteristics may also influence the occurrence of adenomas.Of 62,171 asymptomatic subjects who underwent colonoscopy for a health check-up between 2010 and 2011, 4869 subjects who underwent follow-up colonoscopy between 2012 and 2013 were included in this longitudinal study. The risk of adenoma occurrence was assessed using Cox proportional hazards modeling.Of 4869 subjects, 2827 (58.1%), 1619 (33.3%), and 423 (8.7%) were assigned to the normal, low-risk, and high-risk groups, respectively, according to baseline adenoma characteristics. The mean interval between initial and follow-up colonoscopy was 2.2 ± 0.6 years. Certain patient factors, including older age (≥50 years; adjusted hazard ratio [aHR], 2.08; 95% CI, 1.73–2.49), male sex (aHR, 1.69; 95% CI, 1.30–2.19), metabolic syndrome (MetS) (aHR, 1.28; 95% CI, 1.09–1.51), obesity (aHR, 1.17; 95% CI, 1.02–1.34), elevated fasting blood glucose levels (aHR, 1.37; 95% CI, 1.19–1.58), and elevated triglyceride levels (aHR, 1.19; 95% CI, 1.03–1.37), as well as baseline adenoma characteristics, were associated with a higher risk of adenoma occurrence at follow-up colonoscopy. The cumulative incidence of adenoma occurrence in the high-risk group was higher than that in the low-risk group, whereas the incidence in the high-risk group without MetS was comparable with that in the low-risk group with MetS.Patient characteristics, such as MetS, obesity, older age, and male sex, in addition to adenoma characteristics, were independent risk factors for adenoma occurrence at surveillance colonoscopy. These patient characteristics may be considered in surveillance colonoscopy intervals.

show abstract

Clinical and endoscopic predictors of colorectal adenoma recurrence after colon polypectomy

Abstract: Girifl ve

Cited by 10 publications

References 23 publications

Low rate of advanced adenoma formation during a 5‐year colonoscopy surveillance period after adequate polypectomy of non‐advanced adenoma

Low rate of advanced adenoma formation during a 5‐year colonoscopy surveillance period after adequate polypectomy of non‐advanced adenoma

Adenoma recurrence after endoscopic mucosal resection: propensity score analysis of old and new colonoscopes and Sydney recurrence tool implementation

Metabolic syndrome is a risk factor for adenoma occurrence at surveillance colonoscopy

Contact Info

Product

Resources

About