Clinical and epidemiological profile of childhood vitiligo: analysis of 113 cases diagnosed at a dermatology referral center from 2004 to 2014

Cavalcante, Maria Lopes Lamenha Lins; Pinto, Ana Cecília Versiani Duarte; Brito, Fernanda Freitas de; Silva, Gardênia Viana da; Itimura, Gabriela; Martelli, Antônio Carlos Ceribelli

doi:10.5935/scd1984-8773.201574711

Cited by 2 publications

(2 citation statements)

References 8 publications

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“…The details of each study, including the author’s name, year of publishing, country, sample size, age, gender, type of vitiligo and family history, are summarised in table 1. Concerning the country of study, 11 studies were from Asia,11–21 three were from Europe,22–24 two from America25 26 and one from Africa 27…”

Section: Resultsmentioning

confidence: 99%

Global clinicoepidemiological pattern of childhood vitiligo: a systematic review and meta-analysis

Farajzadeh

Khalili

Mirmohammadkhani

et al. 2023

bmjpo

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BackgroundChildhood vitiligo differs from adult vitiligo in many aspects. To the best of the authors’ knowledge, there is no systematic review of different clinicoepidemiological patterns of vitiligo in children. This study aimed to review the characteristics of vitiligo among the paediatric population.MethodsIn June 2022, a comprehensive search was conducted using MeSh-based keywords on online databases including PubMed, Scopus and Web of Sciences. The papers were assessed, and the eligible articles were selected. The selection of articles followed three distinct steps. The extracted clinicoepidemiological data were then imported into the STATA software for meta-analysis.ResultsThe meta-analysis of 17 studies with 4365 subjects yielded 2475 women (estimated=56.8%, 95% CI 54.45 to 59.22). The female-to-male ratio was determined to be 1.3:1. Meta-regression demonstrated a significant relationship between continents and gender (p=0.03). The most prevalent types of non-segmental vitiligo were vulgaris (42.49%), focal (27.21%) and acrofacial (17.8%). The pooled ratio of non-segmental to segmental was 4.6:1. The highest and lowest ratios were found in Africa with one study (estimated=11.56%, 95% CI −0.98 to 24.10) and America with two studies (estimated=3.02%, 95% CI 1.54 to 4.50), respectively. Using meta-regression, the relationship between continents and vitiligo type was found to be insignificant (p=0.47). Positive family history was recorded in 657 patients (estimated = 16.88%, 95% CI 13.37 to 20.39). Positive family history varied by country of study from 13.91% (Asia with 11 studies) to 27.01% (Europe with two studies) (p=0.11). Kobner phenomena and leukotrichia were noted in 687 (25.47%) and 461 (18.52%) patients, respectively.ConclusionThe review indicated that childhood vitiligo is more prevalent in women. Non-segmental forms of childhood vitiligo were the most common, including vulgaris, focal and acrofacial. The clinicoepidemiological pattern of childhood vitiligo is variable in diﬀerent geographic areas.

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Section: Resultsmentioning

confidence: 99%

Global clinicoepidemiological pattern of childhood vitiligo: a systematic review and meta-analysis

Farajzadeh

Khalili

Mirmohammadkhani

et al. 2023

bmjpo

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“…6 Hasil yang sama ditemukan pada penelitian yang dilakukan di Brazil, lokasi yang paling umum dari manifestasi klinis pertama adalah kepala dengan presentase 27% dan 36% pada tubuh lainnya. 7 Namun tidak ada teori pasti yang mendukung tentang adanya keterkaitan vitiligo dengan jenis kelamin dan usia sehingga pada beberapa penelitian dapat ditemukan hasil yang berbeda.…”

Section: Bahan Dan Metodexxxunclassified

Profil Pasien Vitiligo Di Poli Kulit Kelamin Rumah Sakit Umum Pusat Sanglah Periode 2013 – 2015

Hidayatullah Syukri,

Praharsini

2021

eum

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Vitiligo adalah kelainan kulit yang kronis, ditandai dengan bercak depigmentasi atau hipopigmentasi kulit dan mukosa. Disebabkan oleh berkurangnya jumlah melanosit atau tidak adanya melanosit epidermal pada kulit dan / atau membran mukosa. Rancangan penelitian yang digunakan studi deskriptif cross–sectional (studi prevalensi). Penelitian dilaksanakan di Poli Kulit dan Kelamin Rumah Sakit Umum Pusat Sanglah dari periode Januari 2013 sampai dengan Desember 2015. Berdasarkan hasil penelitian selama 3 tahun terakhir didapatkan 31 penderita vitiligo. Jumlah vitiligo yang berjenis kelamin laki-laki sebanyak 58,1% dan berusia lebih dari 41 tahun sebanyak 27,3%. Pasien yang mengalami durasi lesi 1-5 tahun sebanyak 48,4%. Penderita vitiligo yang mengalami lesi pada kepala sebanyak 42,4%. Penderita vitiligo dengan tipe segmental adalah sebanyak 38,7%. Untuk mengetahui proporsi usia, proporsi jenis kelamin, proporsi lokasi lesi, proporsi durasi lesi, dan tipe lesi pada pasien vitiligo. Dari penelitian disimpulkan pasien vitiligo berusia diatas 40 tahun berjenis kelamin laki – laki dengan durasi lesi selama 1 sampai dengan 5 tahun pada daerah kepala dengan tipe vitiligo segmental. Kata kunci: Vitiligo, usia, jenis kelamin, lokasi lesi, durasi lesi.

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Clinical and epidemiological profile of childhood vitiligo: analysis of 113 cases diagnosed at a dermatology referral center from 2004 to 2014

Cited by 2 publications

References 8 publications

Global clinicoepidemiological pattern of childhood vitiligo: a systematic review and meta-analysis

Global clinicoepidemiological pattern of childhood vitiligo: a systematic review and meta-analysis

Profil Pasien Vitiligo Di Poli Kulit Kelamin Rumah Sakit Umum Pusat Sanglah Periode 2013 – 2015

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