Clinical and histopathological presentations of sinonasal cancers in Komfo Anokye Teaching Hospital

Opoku-Buabeng, J

doi:10.2399/jmu.2016002005

Cited by 5 publications

(5 citation statements)

References 10 publications

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“…Neck-node involvement in Sinonasal malignancy about 10% in our study. In this study observed that 28(70%) patients were found in squamous cell carcinoma, 4(10%) in adenoid cystic carcinoma,3(7.5%) in adenocarcinoma, lymphoma, 1(2.5%) in Olfactory neuroblastoma,1(2.5%) in malignant fibrous histiocytoma and 2(5%) Rhabdomyosarcoma.This is consistent with other studies of home and abroad 8,9,19,20 . In present study observed that intracranial involvement found in 05(12.5%) and orbital involvement in 3(7.5%).…”

Section: Resultssupporting

confidence: 94%

Clinicopathological Study of Sinonasal Malignancy-Experience in a Tertiary Level Hospital in Bangladesh

Hafiz

Rahman

Huda³

et al. 2022

Bangladesh J of Otorhinolaryngology

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Objectives: To assess the clinical presentation and histopathological types and extensions of the disease at the time of presentation. Methods: Cross sectional observational study of 40 patients with sinonasal malignancy from the department of otolaryngology and Head neck surgery, Sylhet MAG Osmani Medical College Hospital, Sylhet Bangladesh, period from May 2019 to April 2020. The patients were examined after admission into hospital pre-operatively and in the postoperative period. The surgical specimens were sent for Histopathology. Results: Majority patients were at 4th to 6th decade where male outnumbered the female with male female ratio was 3.4:1. Out of 40 patients, the majority of patients complaints of nasal obstruction followed by nasal discharge, facial pain, facial swelling and headache. About the site of the lesion maximum patients having the lesion in Maxillary sinus (60%) followed by nasal cavity (15%) multiple sinuses (12.5%) involvement in Ethmoidal sinus (10%) lateral wall of nose (2.5%) Conclusion: Sinonasal Malignancy is usually a disease of middle age and elderly people. Most of the patients (in this study 65% patients come at T3 & T4 stage) presented late with multiple symptoms. Bangladesh J Otorhinolaryngol 2022; 28(1): 37-42

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Section: Resultssupporting

confidence: 94%

Clinicopathological Study of Sinonasal Malignancy-Experience in a Tertiary Level Hospital in Bangladesh

Hafiz

Rahman

Huda³

et al. 2022

Bangladesh J of Otorhinolaryngology

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“…Nasal obstruction, epistaxis and rhinorrhoea were among the commonest clinical features of sinonasal cancers in this study and such findings were similar to what has been documented in studies done elsewhere. [17][18][19] Other clinical features of sinonasal cancers at MNH have been also reported in almost similar fashion to the studies under comparison.…”

Section: Discussionsupporting

confidence: 64%

Clinical Profile of Paediatric Head and Neck Cancers at a Tertiary Hospital in Tanzania

Abraham

Massawe

Kahinga

et al. 2020

RJMHS

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Background Paediatric head and neck cancers represent an important group of childhood cancers that require maximum attention at large. They are often diagnosed at advanced clinical stages at Muhimbili National Hospital (MNH). Objective To describe the clinical profile of paediatric head and neck cancers at a tertiary hospital in Tanzania Method A hospital based descriptive cross-sectional study was conducted involving 180 paediatric patients. Data were analyzed using SPSS program version 21. Results A total of 180 paediatric patients were recruited where 61.1% were males and 38.9% were females. Majority belonged to the age group 0-5 years (53.9%). A total of 10 primary anatomical sites were found with the neck (cervical lymph node) predominating (36.1%), followed by the orbit/eye (34.4%) and the least anatomical sites were oral cavity (1.1%) and parapharyngeal space (0.5%). Leukocoria (93.9%), red eye (93.9%) and orbital cellulitis (77.6%) predominated in retinoblastoma but in patients with lymphomas, predominant features were night sweats (100%), weight loss (100%) and fevers (95.8%). Conclusion The clinical profile depicted in this study appears to correlate with advanced clinical stages. Keywords: Paediatric; Head; Neck Cancers; Muhimbili; Tanzania

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“…Other Studies and reviews done in different parts of the world also showed similar results stating, across all head and neck sites, the most common histology is squamous cell carcinoma, with similar affected age group, gender, risk factors and anatomic site [16,18,19].…”

Section: Statement Of the Problemmentioning

confidence: 53%

Histopathologic study of sinonasal lesions: A hospital based retrospective study, from January 2016 to August 2020

Ruth Abera Alemayehu,

Tufa Gemechu

2023

Int. J. Sci. Res. Updates

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Background: Sinonasal area is a host to various neoplastic and non- neoplastic lesions. The presenting symptoms of sinonasal lesions are similar and pose difficulty for diagnosis based on clinical features and advanced imaging modalities, which makes histopathology the principal diagnostic tool approach for these lesions. The aim of this study is to determine the various histopathologic types of Sinonasal lesions, their classification and relative distribution with regards to age and sex in our setting. Materials and Methods: A retrospective cross-sectional descriptive study conducted on 306 cases of sinonasal lesions over the period from January 2016 to August 2020. All the sinonasal tissues were received and diagnosed at histopathology section of Department of Pathology in Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. The Pathology reports were collected from the pathology data archives; and the variables of study were extracted by using a data extraction sheet, and data analysis was done using SPSS version 26.0. Results: Most affected age group was 21-30 years 81(26.5%). Male predominance was observed with M: F ratio of 1.4:1.Nasal cavity was the commonest anatomical site involved 237(77.5%).There were 137(44.8%) Non-neoplastic lesions and 169(55.2%) Neoplastic lesions. Inflammatory Sinonasal Polyps 100(73.0%) were the most common among non-neoplastic lesions; inverted Sinonasal Papilloma 34(41%) the most common among the benign neoplastic and squamous cell carcinoma and nasopharyngeal carcinoma accounting for 21(25.6%) cases each, were the commonest malignant lesions. Conclusion: clinical findings and advanced image modalities can reach to a presumptive diagnosis for the sinonasal lesions but histopathology remains the gold standard for categorizing and diagnosis of non-neoplastic and neoplastic lesions of sinonasal tract.

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Clinical and histopathological presentations of sinonasal cancers in Komfo Anokye Teaching Hospital

Cited by 5 publications

References 10 publications

Clinicopathological Study of Sinonasal Malignancy-Experience in a Tertiary Level Hospital in Bangladesh

Clinicopathological Study of Sinonasal Malignancy-Experience in a Tertiary Level Hospital in Bangladesh

Clinical Profile of Paediatric Head and Neck Cancers at a Tertiary Hospital in Tanzania

Histopathologic study of sinonasal lesions: A hospital based retrospective study, from January 2016 to August 2020

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