Clinical and Imaging Features of Lacunarand Non-Lacunar Subtypes of Ischemic Posterior Circulation Stroke

Abstract

The aim: The purpose of this study is to determine clinical and imaging features of etiological subtypes of posterior circulation stroke in a prospective hospital-based cohort study. Materials and methods: We prospectively recruited 120 acute posterior circulation stroke patients, admitted to the Neurological Center of the University Hospital (Oleksandrivska Clinical Hospital) in Kyiv, Ukraine, within 6 to 24 hours from the onset of the stroke symptoms. Comprehensive neurological, clinical, laboratory, ultrasound, and imaging examination was performed on all patients. Results: MRI/CT-proven etiological subtypes of ischemic posterior circulation stroke were defined - atherothrombotic (n = 59), cardioembolic (n = 24), lacunar (n = 27), and definitively indeterminate (n = 7). Two main study groups were formed - lacunar (n = 27) and non-lacunar (n = 90) subtypes of posterior circulation stroke. Conclusions: Specific clinical and imaging features of etiological subtypes of posterior circulation stroke were determined, analyzed, compared, and described.

Особливості Нелакунарного Інсульту Варолієвого Моста: Результати Госпітального Проспективного Когортного Дослідження І Презентація Серії Клінічних Випадків У Білих Дорослих Європейців

“…The work is a part of the posterior circulation stroke study. Its settings, parents, definitions, inclusion, and exclusion criteria have been reported in detail previously [12][13][14][15][16][17][18][19][20][21].…”

Клінічні Прояви Гострих Інфарктів Варолієвого Мосту: Огляд

“…Lacunar syndromes in PI are caused by lesions of the corticospinal, corticonuclear, corticopontine, and pontocerebellar tracts and are as follows [11,23].…”

Особливості Лакунарного Інсульту Варолієвого Моста: Результати Госпітального Проспективного Когортного Дослідження

“…Clinical presentation of pontine stroke ranges from the classical crossed syndromes (such as Millard-Gubler, Foville, and Raymond-Cestan) to the less common pure motor, pure sensory stroke, or respiratory and cardiac dysfunction [8][9][10][11][12]. Early diagnosis and adequate understanding of the clinical presentation of LPI are essential for evaluating and managing the disease [13][14][15].…”