Clinical and Imaging Findings of True Hemifacial Hyperplasia

Abstract

Congenital hemifacial hyperplasia is a rare developmental disorder of unknown etiology, characterized by a marked unilateral facial asymmetry. It involves the hard (bones and teeth) and soft tissues of the face. We report an interesting case of true hemifacial hyperplasia in a 25-year-old male highlighting the clinical and computed tomography imaging findings.

Hemifacial hypertrophy: Exploring new avenues of treatment modalities

“…[4567] Idiopathic hemihyperplasia is associated with mild cognitive disability, genitourinary anomalies, and a high association with Wilm's tumor. Our case showed the presence of only an enlarged half of the face with no other part of the body exhibiting asymmetry.…”

“…Deformities of the teeth and their related hard tissues in the jaw are key findings for correct diagnosis, particularly in hemihypertrophy limited to the face. [5]…”

Congenital haemifacial hyperplasia

“…Visit casereports.bmj.com for more articles like this and to become a Fellow Associated abnormalities include thickened skin and hair, excessive secretion of sebaceous and sweat glands, telangiectasias and pigmentary defects on the affected side. 4 Isolated haemifacial hyperplasia is a diagnosis of exclusion. Differentials include other causes of facial asymmetry which include fibro-osseous lesions such as Paget's disease, fibrous dysplasia, dyschondroplasias, vascular malformations and malignant conditions (osteosarcomas, chondrosarcomas).…”

“…These can be differentiated by the presence of foraminal enlargement in haemifacial hyperplasia and characteristic clinic-radiological features in rest of the entities. 4 Other malformation syndromes, such as neurofibromatosis, Proteus syndrome, Beckwith-Wiedemannn syndrome, Epidermal nevus syndrome, Russell-Silver syndrome and Klippel-Trenaunay-Weber syndrome are usually bilateral affecting multiple body parts. Apart from that, unilateral distribution of dental anomalies and concurrent ipsilateral tongue enlargement are unique to haemifacial hyperplasia.…”

Congenital Hemifacial Hyperplasia: Clinical Presentation and Literature Review

“…Rowe [5] proposed a classification of hemihyperplasia based on its anatomic location as (1) simple hemihyperplasia (single limb), (2) complex hemihyperplasia (one-half of the body), and (3) facial hemihyperplasia (one side of the face). Depending on the soft tissue involvement, hemifacial hyperplasia can be broadly classified as (1) true hemifacial hyperplasia (increased growth of one or more tissues on one side of the face) and (2) partial hemifacial hyperplasia (increased growth limited to one structure only) [6]. …”