Clinical and immunological features of oral and vermillion border precancer diseases

Пурсанова, А Е; Kazarina, L.N.; Guschina, O.O.; Serhel, E. V.; Belozyorov, A. E.; Abaev, Z. M.

doi:10.17116/stomat20189705123

Stomat.

2018

DOI: 10.17116/stomat20189705123

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Clinical and immunological features of oral and vermillion border precancer diseases

А Е Пурсанова¹,

L.N. Kazarina²,

O.O. Guschina³

et al.

Abstract: В последние годы, несмотря на появление различных современных методик диагностики и лечения предраковых заболеваний, наблюдается тенденция к их росту. В связи с этим максимально раннее, неинвазивное выявление признаков, способствующих развитию предикторных изменений слизистой оболочки рта (СОР) и красной каймы губ (ККГ), остается актуальной задачей современной стоматологии [2, 5, 10, 11]. В настоящее время появилось достаточно исследований, посвященных связи онкопатологии и вирусных инфекций, изучающих так наз… Show more

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Cited by 5 publications

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Methods of early diagnosis of cancer of the oral mucosa

Kirillova

Павловна²,

Каганов

et al. 2020

Aspirantskiy Vestnik Povolzhiya

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Early diagnosis of cancer of the oral mucosa is still an unsolved problem of current Oncology. Despite the large number of proposed methods of diagnosis of precancerosis and cancer, the incidence of advanced malignant tumors of the oral mucosa are quite high. The analysis of the available scientific articles on the early diagnosis of cancer of the oral mucosa has been performed. The given literature review studies the most common methods of early diagnosis of cancer of the oral mucosa and their availability for practical health care of the Russian Federation.

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Methods of early diagnosis of cancer of the oral mucosa

Kirillova

Павловна²,

Каганов

et al. 2020

Aspirantskiy Vestnik Povolzhiya

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Organization of Screening of Oncostomatological Diseases in the Sverdlovsk Region at the Present Stage

Chernavskiy,

Griroriev,

Kozmenko

et al. 2024

Actual Problems in Dentistry

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Introduction. Since 2012, dentists in the Sverdlovsk region have increasingly been paying attention to the detection of oral diseases at the junction of dentistry and oncology. Oncostomatological disease is a serious threat in everyone's life and leads to a change in the quality of human life, however, their detection in the early stages remained at a fairly low level until the last. There is a high level of oncological diseases in the oral cavity, detected at late stages, which lead to high mortality in both percentage and absolute terms. The experience of our work in 2022–2024 on the territory of the Sverdlovsk region has shown that a significant part of oncostomatological diseases in the population can be identified at an early stage by equipping dentists with means of timely diagnosis of visual localization formations. All precancerous conditions and tumors of the mucous membrane of the mouth, tongue and red border of the lips are visually determined by medical professionals of any specialty. The identification of those tumors that medical professionals (average medical professionals and doctors) can detect at the early stages of the development of the pathological process on the accessible surfaces of the oral cavity and mucous membranes improves the quality of life of our patients. Subject. analysis of factors that reduce the quality and effectiveness of the detection of oncostomatological diseases in the Sverdlovsk region. Aim. To improve the methods of early detection of oral cancer and their prevention. Materials and Methods. A retrospective study of the work of the oncostomatology service in the districts of the Sverdlovsk region was conducted. Results. A program for the early detection and prevention of oncostomatological diseases in the Sverdlovsk region has been created and proposed for practical application. Conclusions. The lack of standardization of approaches to identifying and recording precancerous and cancerous diseases at the stages of providing primary health care, the lack of personnel with the skills to identify oncological diseases, are one of the factors for the low effectiveness of pathology detection. In dentistry, there are no clinical recommendations regulating the procedure for examining and treating patients with malignant neoplasms.

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Refinement of noninvasive methods for diagnosing precancer and cancer of oral mucosa in general dental practice

Postnikov

Gabrielyan

Trunin

et al. 2021

BRSMU

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The search for and the application of available noninvasive methods for early diagnosis of oral mucosa (OM) neoplasia is a clinically significant problem. The aim of this study was to evaluate the effectiveness of the original score-based algorithm for assessing clinical data generated by a conventional and an autofluorescencebased examination in diagnosing OM cancer and assessing indications for a biopsy. We analyzed 134 medical histories and pathology reports of patients with oral neoplasia. The patients were assigned to 2 groups: the control group included 63 patients who underwent a standard visual and tactile examination with history taking and then were referred for an incisional biopsy followed by a histopathological examination of the specimens. In the main group consisting of 71 patients, a standard visual and tactile examination was complemented by an autofluorescence-based examination and the original score-based algorithm with the original index of required histopathological verification (RHV) were used to assess indications for a biopsy. In both groups, the most commonly affected site was the tongue (72.4%). The histopathological examination revealed that 28 patients from the main group and 14 patients from the control group had OM cancer (р = 0.051). Histologically, early-stage cancer was diagnosed in 17 patients from the main group and in 4 patients from the control group (р = 0.004). The proposed algorithm allowed us to effectively (in 90% of cases) diagnose precancer and cancer and avoid unnecessary biopsies.

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Clinical and immunological features of oral and vermillion border precancer diseases

Cited by 5 publications

References 2 publications

Methods of early diagnosis of cancer of the oral mucosa

Methods of early diagnosis of cancer of the oral mucosa

Organization of Screening of Oncostomatological Diseases in the Sverdlovsk Region at the Present Stage

Refinement of noninvasive methods for diagnosing precancer and cancer of oral mucosa in general dental practice

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