Clinical and immunological parameters of Sjögren's syndrome

Ψιάνου, Κωνσταντία; Panagoulias, Ioannis; Papanastasiou, Anastasios D.; Lastic, Anne-Lise de; Rodi, Maria; Spantidea, Panagiota I.; Degn, Søren E.; Georgiou, Panagiotis; Mouzaki, Αthanasia

doi:10.1016/j.autrev.2018.05.005

Cited by 128 publications

(98 citation statements)

References 154 publications

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“…Other new associations include the association of rheumatoid arthritis autoantibodies with intrinsic lung disease, the long-term pulmonary mortality risks associated with IgA anti-TTG, and the possible trans-placental effects of thyroid autoantibodies [76][77][78][79][80][81]. These discoveries of new health outcome associations should be expected, as autoimmune diseases have diverse, protean manifestations, such as the wide-ranging clinical manifestations of systemic lupus erythematosus, celiac disease, dermatomyositis, Sjogren's syndrome, and multiple sclerosis, among others [12,13].…”

Section: Discussionmentioning

confidence: 99%

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Population-based estimates of humoral autoimmunity from the U.S. National Health and Nutrition Examination Surveys, 1960–2014

2020

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ObjectiveBased on US National Health and Nutrition Examination Survey (NHANES) data, we attempted to provide an unbiased, population-based estimate of autoantibody prevalence overall and by age and sex. MethodsUS autoantibody prevalence estimates for detectable rheumatoid factor, anti-thyroglobulin, anti-thyroperoxidase, anti-transglutaminase, anti-endomysial, anti-GAD65, antinuclear autoantibodies, and autoantibodies to extractable nuclear antigens were estimated from the 1960-1962 National Health Examination Survey, NHANES III (1988, and the NHANES 1999-2014 cross-sectional surveys. Survey design variables and sample weights were used to account for differential probabilities of selection within the complex survey design. Data analysis used SAS TM and SUDAAN™ software. US Census Bureau data were used to estimate the absolute numbers of persons with autoantibodies.

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Section: Discussionmentioning

confidence: 99%

“…Epidemiological research, however, has shown that autoimmune disorders are common, have genetic links among one another, and can overlap or even evolve from one clinical phenotype to another [10][11][12][13]. An estimated 3-7% of the general population has an AID, depending on the specific AIDs studied [10,11,14].…”

Section: Introductionmentioning

confidence: 99%

Population-based estimates of humoral autoimmunity from the U.S. National Health and Nutrition Examination Surveys, 1960–2014

2020

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“…SjS pathogenesis occurs through a combination of genetic, environmental, and hormonal factors, leading to the development of inflammation and autoimmune responses to the exocrine glands [26]. There are two variants of SjS; primarywhich occurs in isolation without other systemic autoimmune diseases; and secondary which occurs following a diagnosis of systemic autoimmune disease; most commonly RA.…”

Section: Sjögren's Syndromementioning

confidence: 99%

“…The commonly cited auto-antibodies in SjS are antigens against La/SSB/TRIM21 and Ro60/TROVE2. As such, these act as important diagnostic markers for SjS [26].…”

Section: Sjögren's Syndromementioning

confidence: 99%

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Autoimmunity and the Oral Cavity

Reilly

Johnston

Culshaw

2019

Curr Oral Health Rep

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Purpose of Review This review aims to make the oral health practitioner and researcher aware of autoimmune diseases that present in the mouth and have implications for oral health. Specifically, the autoimmune pathophysiology, examples of treatments, sequelae, and impact on oral health will be discussed. The limitations of our current knowledge and understanding of these diseases will also be highlighted. Recent Findings Over the past decade, it has become clear that there is a bidirectional relationship between oral health and autoimmune disease at other body sites; including diabetes and rheumatoid arthritis. Improving the oral health of patients with autoimmune diseases may reduce morbidity associated with such diseases. Summary Autoimmune diseases impact the oral cavity both directly and indirectly and are increasing in prevalence. As such, there is a growing need for the oral health practitioners to be aware of how autoimmune disease impacts the oral cavity. Further research is necessary to improve our understanding of the bidirectional relationship between oral health and autoimmune disease.

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Sjögren's Syndrome as a Proof of Concept of the Hyperstimulation Syndrome

Borba,

Shoenfeld

2024

Autoimmune Disorders

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Clinical and immunological parameters of Sjögren's syndrome

Cited by 128 publications

References 154 publications

Population-based estimates of humoral autoimmunity from the U.S. National Health and Nutrition Examination Surveys, 1960–2014

Population-based estimates of humoral autoimmunity from the U.S. National Health and Nutrition Examination Surveys, 1960–2014

Autoimmunity and the Oral Cavity

Sjögren's Syndrome as a Proof of Concept of the Hyperstimulation Syndrome

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